The prevalence of chronic kidney disease (CKD) is rising every year, and traditional Chinesemedicine (TCM) has cer-tain advantages for treating CKD. "Unobstruction" is the physiological state while "obstruction" is the pathological state of human body. Obstruction-removing therapy is an essentialmethod in TCM treatment principles, which includes reductionmethod (xie-tong) and reinforcementmethod (bu-tong). The formermeans that the prescriptions have the effect of dredging stagnation, while the latter refers to the effect of reinforcing healthy qi. Professor Zhang Bing-hou considered the pathological factor of CKD was deficiency-ex-cess in complexity, with the basic pathogenesis of deficiency of spleen and kidney and kidney collateral stasis. He proposed the treatment of CKD should, on the basis of tonifying the kidney, emphasize the use of obstruction-removing therapy and themethod of dispersing wind, dredging collaterals, clearing heat, resolving dampness, promoting blood circulation and dredging meridians based on differentiation. Membranous nephropathy ismostlymanifested as nephrotic syndrome, especially under hypercoagulable state and easily contributed to thrombosis formation. Its treatment should focus on promoting blood circulation and dredging meridian with commonly used Persicae Semen, Carthami Flos, Ramulus Euonymi, Sparganii Rhizoma, Curcumae Rhizoma, and Hirudo. The promi-nent pathogenesis of HBV-associated renal disease is dampness-heat, which ismanifested as abdominal fullness and distention, fa-tigue and tiredness, poor stoolwith incomplete evacuation, and foamy urine. Its treatment should base on clearing heatand resolving dampness, with commonly used raw Coicis Semen, Amomum cardamomum, Pogostemonis Herba, Eupatorii Herba and Hedyotidis Herba. IgA nephropathy is easily being invaded by exogenous pathogen and tends to recur. Its treatment should base on dispelling wind, with commonly used Charred Schizonepeta, Saposhnikoviae Radix, Lonicerae Japonicae Flos and Forsythiae Fructus. Professor Zhang is good atusing insect drugs, such as Scorpio, Scolopendra, Bombyx Batryticatus, and Hirudo, in the treatmentof CKD. Addi-tionally, he pays attention to the combination of disease differentiation and stages.