Endometrial thickening is a non-physiological endometrial gland hyperplasia in women. It is regarded as a precancerous lesion of endometrial cancer. It has become more and more common in women in recent years. It is clinically characterized by abnormal uterine bleeding, abnormal vaginal discharge or Symptoms such as lower abdomen pain are more common. According to their clinical manifestations, they belong to the category of Chinese medicine metrorrhagia. At present, the diagnostic standards for endometrial hyperplasia diseases at home and abroad have not been unified, and the treatment is also lacking in standardization. Professor Yang Zhengwang found that the adolescent endometrial thickening syndrome is the most common clinically with kidney deficiency and blood stasis syndrome. The treatment is mainly to invigorate the liver and kidney, supplemented by activating blood to remove blood stasis, and adding and subtracting Dabuyuan decoction. The clinical effect is good. This article focuses on the clinical experience of Dabuyuan decoction in the treatment of endometrial thickening in order to provide traditional Chinese medicine diagnosis and treatment ideas.