1.北京中医药大学，北京 100029
2.中国中医科学院广安门医院，北京 100053
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曹晔文, 曹炜, 王欣妍, 等. 曹炜从“痰瘀同治”辨治类风湿关节炎伴脂代谢异常[DB/OL].（2023-09-15）[2023-11-05].http://cccl-tcm.cacm.org.cn/thesisDetails#10.19945/j.cnki.issn.1006-3250.2021.05.033
Ye-wen CAO, Wei CAO, Xin-yan WANG, et al. Experience of CAO Wei in Treating Rheumatoid Arthritis Complicated with Abnormal Lipid Metabolism by The Theory of Removing Phlegm and Blood Stasis Simultaneously[DB/OL].（2023-09-15）[2023-11-05].http://cccl-tcm.cacm.org.cn/thesisDetails#10.19945/j.cnki.issn.1006-3250.2021.05.033
曹晔文, 曹炜, 王欣妍, 等. 曹炜从“痰瘀同治”辨治类风湿关节炎伴脂代谢异常[DB/OL].（2023-09-15）[2023-11-05].http://cccl-tcm.cacm.org.cn/thesisDetails#10.19945/j.cnki.issn.1006-3250.2021.05.033 DOI：
Ye-wen CAO, Wei CAO, Xin-yan WANG, et al. Experience of CAO Wei in Treating Rheumatoid Arthritis Complicated with Abnormal Lipid Metabolism by The Theory of Removing Phlegm and Blood Stasis Simultaneously[DB/OL].（2023-09-15）[2023-11-05].http://cccl-tcm.cacm.org.cn/thesisDetails#10.19945/j.cnki.issn.1006-3250.2021.05.033 DOI：
脂代谢异常是类风湿关节炎临床常见的并发症，其发病率高、早期症状隐匿，是诱发心脑血管疾病的重要危险因素，可能与患者长期使用抗风湿类药物、缺少运动以及类风湿关节炎本身炎症活动有关，二者相互影响，病程迁延，严重影响病人生活质量类。风湿关节炎伴脂代谢异常与痰瘀联系密切，痰瘀既是贯通疾病全程的病理产物，也是本病进一步加重的病理要素。痰瘀皆由水谷精微转化而来，由气机调控与营卫失和相关。曹炜教授认为营卫不和、痰瘀互结是本病发病的病理基础，并在多年的临床实践中，重视“痰瘀同治”的治疗原则以及当代人体质变化特点，用药时并重祛痰化瘀、清热祛湿、祛风通络、疏调气机、滋肾健脾等原则，注重用药时机，临床治疗效果颇佳。
Abnormal lipid metabolism is a common complication of rheumatoid arthritis, which is a significant risk factor for cardiovascular and cerebrovascular diseases.It has a high morbidity and it is hard to be diagnosed.It may be related to the long-term use of antirheumatic drugs, lack of exercise and inflammatory activity of rheumatoid arthritis.The two diseases influence each other and affect the life quality of patients seriously.Rheumatoid arthritis with abnormal lipid metabolism is closely related to phlegm and blood stasis.Phlegm and blood stasis are not only pathological products throughout the whole course of the disease, but also pathological factors for the disease.Phlegm and blood stasis are all slightly transformed from cereal essence, regulated by Qi, and related to the disharmony of Ying and Wei.Professor Cao Wei believes that the discord between Ying and Wei, the accumulation of phlegm and blood stasis are the pathological basis of the disease.In clinical practice, we paid attention to the treatment principle of “remove the phlegm and blood stasis simultaneously“ and the characteristics of physical changes of contemporary people.Some principles were important in clinical practice, which include expelling phlegm and removing blood stasis, clearing heat and dampness, dispelling wind and dredging collaterals, dredging qi-activity and nourishing kidney and spleen.The treatment effect was proved.
类风湿关节炎脂代谢异常痰瘀同治中医治疗痹证
Rheumatoid arthritisAbnormal lipid metabolismSimultaneous treatment of phlegm and blood stasisTraditional Chinese medicine treatmentBi syndrome
高莉，贾园，刘萍，等.类风湿关节炎患者91例死亡原因及预后因素分析[J].中华风湿病学杂志，2013,17(8):542-545.
周珍妮，李芳，黄德益，等.类风湿关节炎患者223例共病现象的临床特征及其相关因素分析[J].中国全科医学，2017,20(18):2201-2207.
PLUTZKY J, LIAO KP.Lipids in RA:Is Less Not Necessarily More?[J].Curr Rheumatol Rep，2018,20(2):8.
MYASOEDOVA E, GABRIEL SE, GREEN AB, et al.Impact of statin use on lipid levels in statin-naive patients with rheumatoid arthritis versus non-rheumatoid arthritis subjects:results from a population-based study[J].Arthritis Care Res(Hoboken)，2013,65(10):1592-1599.
路志正，焦树德.实用中医风湿病学[M].北京:人民卫生出版社，1996:5.
张从正.儒门事亲[M].刘更生，点校.天津:天津科学技术出版社，1999:8.
张介宾.景岳全书[M].北京:中国中医药出版社，1994:144-363.
张秉成.成方便读[M].北京:科技卫生出版社，1958:110.
张景岳.类经[M].范志霞，校注.北京:中国医药科技出版社，2011:47.
赵佶.圣济总录[M].北京:人民卫生出版社，1962:67.
叶天士.临证指南医案[M].华岫云，编订.北京:华夏出版社，1995:402.
唐宗海.血证论[M].欧阳兵，等点校.天津:天津科学技术出版社，2003:84.
何梦瑶.医碥[M].北京:中国中医药出版社，2009:175.
鲁明源.现代生活方式与人类体质演化[J].山东中医药大学学报，2002,26(1):48-52.
石英杰，姜泉，殷海波.类风湿关节炎活动期湿热瘀阻病机探讨[J].北京中医药，2009,28(5):344-346.
智恺，刘春芳，曹炜，等.清热活血方对肿瘤坏死因子α诱导的类风湿关节炎成纤维样滑膜细胞迁移和黏附的影响[J].中医杂志，2016,57(20):1777-1781.
王好古.汤液本草[M].崔扫麈，尤荣辑，点校.北京:人民卫生出版社，1987:24-81.
左军，牟景光，胡晓阳.半夏化学成分及现代药理作用研究进展[J].辽宁中医药大学学报，2019,21(9):26-29.
KIM YJ, SHIN YO, HA YW, et al.Anti-obesity effect of Pinellia ternata extract in Zucker rats[J].Biol.Pharm.Bull，2006,29(6):1278-1281.
唐慎微.证类本草·重修政和经史证类备急本草[M].尚志钧，等校点.北京:华夏出版社，1993:384.
张秉成.本草便读[M].上海:上海卫生出版社，1958:35.
WANG Y, YU C, ZHANG H.Lipopolysaccharides-mediated injury to chondrogenic ATDC5 cells can be relieved by Sinomenine via downregulating microRNA-192[J].Phytother Res，2019,33(7):1827-1836.
缪希雍.神农本草经疏[M].太原:山西科学技术出版社，2013:140-162.
张璐.本经逢原[M].赵小青，裴晓峰，校注.北京:中国中医药出版社，1996:85.
MA D, LI Y, XIAO W, et al.Achyranthes bidentata extract protects chondrocytes functions through suppressing glycolysis and apoptosis via MAPK/AKT signaling axis[J].American journal of translational research，2020,12(1):142-152.
童琦燕.牛膝治疗高尿酸血症高脂血症[J].辽宁中医杂志，2003,30(11):943.
中国成人血脂异常防治指南修订联合委员会.中国成人血脂异常防治指南(2016年修订版)[J].中华健康管理学杂志，2017,11(1):7-28.
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