Professor Yang Zhi-bo believes that the pathogenesis of rose acea is "internal heat attack", while emotional disorder, improper diet and excessive sun exposure are important factors inducing "blood heat accumulation". Professor Yang believes that rose acne initially occurs in the lung and should be prevented in the early stage. Pipaye (,Folium Eriobotryae,), Sangye (,Folium Mori,), Huangqin (,Radix Scutellariae,), Sangbaipi (,Cortex Mori,), Baimaogen (,Rhizoma Imperatae,), Baihuasheshecao (,Herba Hedyotis Diffusae,), Jinyinhua (,Flos Lonicerae Japonicae,), etc., can be used to dispel wind and clear heat, detoxify and ventilate the lung. If irritability, poor sleep and red tongue tip are also seen, Zhizi (,Fructus Gardeniae,) and Lianzixin (,Plumula Nelumbinis,) are add-ed to clear the heart fire, and Hehuanpi (,Cortex Albiziae,) is used to relieve depression and calm the mind. At the same time, Danzhuye (,Herba Lophatheri,) and Dengxincao (,Medulla Junci,) are used to induce the heart fire from urination, so that the patho-gens can have a way out. On the basis of clearing the "spleen heat" , "acquired foundation" should be paid attention to, Dangshen (,Radix Codonopsis,), Baizhu (,Rhizoma Atractylodis Macrocephalae,), Yiyiren (,Semen Coicis,), Fuling (,Poria,), Shanyao (,Rhizoma Dioscoreae,), etc. can be adopted. In order to avoid the source of generation and transformation of dampness-heat, the patients should be far away from "volatiles." Rose acne is common in middle-aged women. It is treated with soothing the liver and relieving depression, clearing heat and cooling blood, combined with regulating emotions, nourishing and softening the liver. Chaihu (,Radix Bupleuri,), Meiguihua (,Flos Rosae Rugosae,), Xiangfu (,Rhizoma Cyperi,), Baishao (,Radix Paeoniae Alba,), Zhizi (,Fructus Gar-deniae,), Mudanpi (,Cortex Moutan,), Chishao (,Radix Paeoniae Rubra,), etc. are widely used in clinical practice. In the later stage of rose acne, the blood heat of nutrient ,qi, is abundant, the pathogenic heat enters the collaterals,qi, and blood are stagnant, and the phlegm, dampness, blood stasis and heat are intermingled. Modified Peach Kernel and Carthamus Four Substances Decoction can be used. Xiakucao (,Spica Prunellae,), Zaojiaci (,Spina Gleditsiae,) can be added to soften hard lump, break blood stasis and elimi-nating abdominal mass; Chenpi (,Pericarpium Citri Reticulatae,) and Zhebeimu (,Bulbus Fritillariae Thunbergii,) can be added to resolve phlegm and remove dampness. Professor Yang believes that the symptoms of facial dryness and the pathogenesis of yin deficiency and blood heat run through the beginning and end of rose acne. In terms of treatment, we should give consideration to nourishing yin and ,qi, to regulate the essence and protect the healthy ,qi,. The whole course of the disease should pay attention to clearing heat and cooling blood, moistening dryness and nourishing yin. Clinically, Lugen (,Rhizoma Phragmitis,), Yuzhu (), Mudanpi (,Cortex Moutan,), Xuanshen (,Radix Scrophulariae,), Shanshashen (,Radix Adenophorae,), Maidong (,Radix Ophiopogonis,), Dansh-en (,Radix Salviae Miltiorrhizae,), Chishao (,Radix Paeoniae Rubra,), Baishao (,Radix Paeoniae Alba,), Tiepishihu (,Caulis Dendro-bii,), etc. can be often used to cool blood and nourishing yin. Tiepishihu (,Caulis Dendrobii,) is especially widely adopted. Professor Yang believes that nature and human body are inseparable and are an organic whole. Based on the "unity of heaven and man" and "medicine image theory" , he puts forward the theories of "treating skin with skin" and "nourishing body with flowers". In the treatment of rose acne based on syndrome differentiation, he pays more attention to treating manifestation and root cause, the interior and exterior concurrently.