仝小林运用蒲公英、白花蛇舌草、山茱萸治疗湿热蕴结型肠上皮化生经验
Professor Tong Xiaolin’s experience in treating intestinal metaplasia of dampness-heat stagnation type with dandelion, hedyotis, asiatic cornelian cherry fruit
DOI:10.13463/j.cnki.jlzyy.2021.01.007
扫 描 看 全 文
1.广州中医药大学深圳医院<福田>仝小林学术传承工作室,广东 深圳 518034
扫 描 看 全 文
顾成娟, 杨才佳, 吴学敏. 仝小林运用蒲公英、白花蛇舌草、山茱萸治疗湿热蕴结型肠上皮化生经验[DB/OL].(2023-09-15)[2023-11-05].http://cccl-tcm.cacm.org.cn/thesisDetails#10.13463/j.cnki.jlzyy.2021.01.007
GU Chengjuan, YANG Caijia, WU Xuemin. Professor Tong Xiaolin’s experience in treating intestinal metaplasia of dampness-heat stagnation type with dandelion, hedyotis, asiatic cornelian cherry fruit[DB/OL].(2023-09-15)[2023-11-05].http://cccl-tcm.cacm.org.cn/thesisDetails#10.13463/j.cnki.jlzyy.2021.01.007
顾成娟, 杨才佳, 吴学敏. 仝小林运用蒲公英、白花蛇舌草、山茱萸治疗湿热蕴结型肠上皮化生经验[DB/OL].(2023-09-15)[2023-11-05].http://cccl-tcm.cacm.org.cn/thesisDetails#10.13463/j.cnki.jlzyy.2021.01.007 DOI:
GU Chengjuan, YANG Caijia, WU Xuemin. Professor Tong Xiaolin’s experience in treating intestinal metaplasia of dampness-heat stagnation type with dandelion, hedyotis, asiatic cornelian cherry fruit[DB/OL].(2023-09-15)[2023-11-05].http://cccl-tcm.cacm.org.cn/thesisDetails#10.13463/j.cnki.jlzyy.2021.01.007 DOI:
仝小林院士认为,胃黏膜肠上皮化生为癌前病变,应当重点关注,治疗具有重要意义。湿热蕴结型是肠上皮化生的常见类型之一,多因饮食不调,久食膏粱厚味,日久酿生湿热,内蕴脾胃而引起,亦可因感受湿热交阻于中焦而致病。胃喜润恶燥,治疗要点一为改善胃内湿热环境,改善黏膜生存状态,使其滋润;二为保护消化道黏膜,不局限于胃黏膜;三是仍需要继续寻找针对某一靶点的特效药。仝小林临床常使用蒲公英、白花蛇舌草、山茱萸为基础方配伍治疗此病。蒲公英、白花蛇舌草以清泻胃热,解毒利湿,切断来路,二药均为甘凉之品,燥湿而不伤胃阴;山茱萸为治疗肠上皮化生的经验用药。方中蒲公英常用剂量为15~30 g,白花蛇舌草常用剂量为9~15 g,山茱萸常用剂量为9~30 g。
Academician Tong Xiaolin believes that intestinal metaplasia of gastric mucosa is a precancerous lesion,which should be paid more attention to and whose treatment is of great signi fi cance. Intestinal metaplasia of dampnessheat stagnation type, one of its common types, is often caused by disharmony of diet, long-term excessive intake of fatty diet with rich fl avour, which in turn generates dampness and heat over time and accumulates them in spleen and stomach. It can also be caused by feeling the obstruction of dampness and heat in the middle jiao. Traditional Chinese medicine believes that stomach prefers moisture to dryness. According to Academician Tong Xiaolin, the key points of treatment are as follows: fi rst, improve the humid and hot environment in the stomach, improve the survival state of the mucosa and make it moisturized; second, protect the digestive tract mucosa in addition to the gastric mucosa;third, continue to look for speci fi c drugs for a certain target. In clinical practice, Academician Tong Xiaolin often uses dandelion, hedyotis, asiatic cornelian cherry fruit to make up a minor basic prescription to treat this disease. Dandelion and hedyotis are used for clearing stomach heat, resolving toxins and removing dampness, thus cutting o ff the origin of pathogenic factors. The two medicines are both sweet and cool, which can dry dampness without damaging stomach yin. Asiatic cornelian cherry fruit is an empirical medicine for the treatment of intestinal metaplasia. The common dosage of the three medicines is 15-30 g, 9-15 g and 9-30 g respectively.
湿热蕴结型肠上皮化生蒲公英白花蛇舌草山茱萸仝小林
intestinal metaplasia of dampness-heat stagnation typedandelionhedyotisasiatic cornelian cherry fruitTong Xiaolin
DE VRIES A C, KUIPERS E J. Epidemiology of premalignant gastric lesions: implications for the development of screening and surveillance strategies[J]. Helicobacter, 2007, 12 Suppl 2:22-31. DOI: 10.1111/j.1523-5378.2007.00562.xhttp://doi.org/10.1111/j.1523-5378.2007.00562.x.
柳云婷,刘敏,李强,等.胃黏膜肠上皮化生研究现状[J].胃肠病学和肝病学杂志, 2019, 28(10):1169-1173.
李枝锦,吴平财.慢性萎缩性胃炎的微观辨证研究进展[J].中国中西医结合消化杂志, 2020, 28(1):72-76.
仝小林,何莉莎,赵林华.论“态靶因果”中医临床辨治方略[J].中医杂志, 2015, 56(17):1441-1444.
谢士敏,周长征.蒲公英药理作用及临床应用研究进展[J].辽宁中医药大学学报, 2020, 22(5):138-142.
LU B, CHEN M T, FAN Y H, et al. Effects of Helicobacter pylori eradication on atrophic gastritis and intestinal metaplasia: a 3-year follow-up study[J]. World J Gastroenterol,2005, 11(41):6518-6520. DOI: 10.3748/wjg.v11.i41.6518http://doi.org/10.3748/wjg.v11.i41.6518.
纪宝玉,范崇庆,裴莉昕,等.白花蛇舌草的化学成分及药理作用研究进展[J].中国实验方剂学杂志, 2014,20(19):235-240.
周迎春,张廉洁,张燕丽.山茱萸化学成分及药理作用研究新进展[J].中医药信息, 2020, 37(1):114-120.
国家药典委员会.中华人民共和国药典:一部[M].北京:中国医药科技出版社, 2015.
0
浏览量
7
下载量
0
CSCD
关联资源
相关文章
相关作者
相关机构