Chronic cholecystitis belongs to gallbladder distention in traditional Chinese medicine, which has a long course of disease. Western medicine treatment of this disease often takes symptomatic treatment, and long-term use of Western medicine has a certain risk of side effects. After years of experience and clinical practice, traditional Chinese medicine treatment of this disease is feasible, with few side effects. Professor XIE Jingri has been working in clinic for 40 years. After continuous summary, he has put forward the idea of "liver and spleen theory", and has made a lot of researches on digestive diseases. Professor XIE thinks that "the liver is the general in the middle, influenced by the gallbladder". The liver and the gallbladder interact each other, and they are closely related in physiology and pathology. "Spleen and stomach injury can cause all kinds of diseases". Spleen and stomach is the source of the body's healthy Qi. Protecting spleen and stomach can achieve the purpose of "consolidating healthy Qi and expelling evils". Therefore, the treatment of "gall distension" should take the relationship among Zang-Fu organs. The purpose of this paper is to expound Professor XIE Jingri's clinical experience on treating chronic cholecystitis from liver and spleen and stomach.