acupuncture has been widely recognized in clinical treatment of depression, but the doctors have different understanding of the disease. Sheng acupuncture believes that the disease of depression is causedby disharmony in the internal and external boundaries of human body, the pathogenesis of which is the damage of Qi and blood function of viscera, blood stasis, phlegm dampness and other pathogenic factors, and the damage of Yang Qi, damage of gods and abnormal spirits. In view of the origin of pathogenic and yang deficiency, Sheng acupuncture put forward the acupuncture method of "regulating Yang and eliminating evil spirits" to treat depression. The paper analyzes the basis of acupuncture points selection and acupuncture technique of "regulating Yang and removing evil factors" in Sheng, and provides a new way of thinking for clinical diagnosis and treatment.