中医理论指导下整合治疗晚期宫颈癌1例
Integrated Treatment of Advanced Cervical Cancer Under the Guidance of Traditional Chinese Medicine Theory: A Case Report
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1.北京中医药大学深圳医院<龙岗>,广东深圳518172
2.北京中医大学东方医院,北京 100078
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冯高飞,彭昭文,孙小梅,等.中医理论指导下整合治疗晚期宫颈癌1例[DB/OL].(2023-11-13)[2023-11-13].http://cccl-tcm.cacm.org.cn/thesisDetails?columnId=43868785&Fpath=home&index=0&lang=zh
FENG Gaofei,PENG Zhaowen,SUN Xiaomei,et al.Integrated Treatment of Advanced Cervical Cancer Under the Guidance of Traditional Chinese Medicine Theory: A Case Report[J].,
冯高飞,彭昭文,孙小梅,等.中医理论指导下整合治疗晚期宫颈癌1例[DB/OL].(2023-11-13)[2023-11-13].http://cccl-tcm.cacm.org.cn/thesisDetails?columnId=43868785&Fpath=home&index=0&lang=zh DOI:
FENG Gaofei,PENG Zhaowen,SUN Xiaomei,et al.Integrated Treatment of Advanced Cervical Cancer Under the Guidance of Traditional Chinese Medicine Theory: A Case Report[J]., DOI:.
病史摘要,2,主诉:发现宫颈癌4年余,复发伴会阴部及肝区疼痛3月。关键病史:2014年9月出现阴道不规则出血,即行宫颈全切术,术后病理为鳞癌。2019年3月出现尿频尿急尿血,行PET-CT提示宫颈癌复发并多发转移,行手术治疗。术后3月出现会阴部及肝区疼痛,应用止痛药物效果不佳,于我科住院治疗。刻下症:神清,精神疲乏,全身乏力,上腹部及会阴部疼痛,可见阴道血性分泌物,纳差,眠可,大便不畅,肾造瘘引流尿液通畅。中医四诊:神志清楚,精神疲乏,面色欠润,双目乏神,皮肤暗沉,舌淡紫,苔白腻,脉滑。辅助检查:2019年6月5日全腹CT示阴道残端肿瘤复发,肝脏多发转移并累及胆囊,左肺下叶转移。中医诊断 癥瘕(痰瘀互结证)。西医诊断 宫颈中分化鳞癌,cTxNxM1,IVB期,肺转移,肝转移,多发淋巴结转移,阴道残端复发,膀胱直肠阴道侵犯切除术后。干预措施 在中医理论指导下接受中医药、消融、化疗、免疫治疗等的整合治疗。疗效转归 达到了肿瘤的稳定及生活质量的提高,并显著延长了该患者的生存期。
Summary of case history, Complaint: cervical cancer was found more than 4 years ago, recurrence with pain in perineum and liver area for 3 months. Key medical history: irregular vaginal bleeding appeared in September 2014, that is, total cervical excision was performed, and the postoperative pathology was squamous carcinoma. frequency of urination and urgency of urination and blood in urine appeared in March 2019, and PET-CT was performed to suggest that the cervical cancer was recurrent with multiple metastases, and surgical treatment was performed. In March after the operation, pain in perineum and liver area appeared, and the application of pain-relieving drugs was ineffective, so she was hospitalized in our department. Symptoms: clear consciousness, mental fatigue, generalized weakness, epigastric and perineal pain, visible vaginal bloody discharge, poor appetite, sleep, poor bowel movement, smooth urine drainage from nephrostomy. Chinese medicine quadruple diagnosis: clear consciousness, mental fatigue, face color is not moist, eyes are lack of spirit, skin is dark, tongue is light purple, moss is white and greasy, pulse is smooth. Auxiliary examination: whole abdomen CT on June 5, 2019 showed tumor recurrence in the vaginal stump, multiple liver metastases with gallbladder involvement, and metastases in the lower lobe of the left lung.,TCM diagnosis, Mass obstruction (phlegm and blood stasis syndrome),Western medicine diagnosis, Moderately differentiated squamous carcinoma of the uterine cervix (cTxNxM1 IVB, lung metastases, liver metastases, multiple lymph node metastases, recurrence of the vaginal stump, cysto-rectovaginal invasion post resection),Therapeutic methods, Receive integrated treatment with TCM, ablation, chemotherapy and immunotherapy under the guidance of TCM theory.,Clinical outcomes, Tumor stabilization and quality of life were achieved and significantly prolonged this patient's survival.
宫颈癌中医理论整合治疗
Cervical cancerTraditional Chinese medicine theoryIntegrated treatment
Sung H,Ferlay J,Siegel RL,et al.Global Cancer Statistics 2020:GLOBOCAN Estimates of incidence and mortality worldwide for 36 cancers in 185 countries[J].CA Cancer J Clin,2021,71:209-249.
Cohen PA,Jhingran A,Oaknin A,et al.Cervical cancer[J].Lancet,2019,393:169-182.
CHUNG H C, ROS W, DELORD J P, et al. Efficacy and Safety of Pembrolizumab in Previously Treated Advanced Cervical Cancer: Results From the Phase ⅡKEYNOTE-158 Study[J]. JClin Oncol, 2019, 37(17):1470-1478.
Tseng M, Ngoi NY, Tan DS, et al.Combined modality management of advanced cervical cancer including novel sensitizers[J].International Journal of Gynecologic Cancer,2022,32:246-259.
Simha V,Rai B,Patel F D,et al.Clinical outcomes with MRI-guided image-based brachytherapy in cervical cancer:an institutional experience[J].Brachytherapy,2018,17(2):345-51.
Della Corte L, Barra F, Foreste V, et al. Advances in paclitaxel combinations for treating cervical cancer[J]. Expert Opin Pharmacother. 2020, 21(6):663-677.
Suh DH, Kim M, Lee KH, et al. Major clinical research advances in gynecologic cancer in 2017[J]. J Gynecol Oncol, 2018, 29(2):1-18.
4thSkelton WP, Castagno J, Cardenas-Goicoechea J, et al. Bevacizumab eligibility in patients with metastatic and recurrent cervical cancer: a retrospective review[J]. Clin Med Insights Oncol, 2018, 20(7):922-927.
Kitagawa R, Katsumata N, Shibata T, et al. Paclitaxel plus carboplatin versus paclitaxel plus cisplatin in metastatic or recurrent cervical cancer: the open-label randomized phase Ⅲ trial JCOG0505[J]. J Clin Oncol, 2015, 33(19):2129-2135.
Tewari KS, Sill MW, Birrer MJ, et al. Final survival analysis of topotecan and paclitaxel for first-line treatment of advanced cervical cancer: An NRG oncology randomized study[J]. Gynecol Oncol. 2023, 171:141-150.
陈兰玉, 胡凯文. 基于PD-1/PD-L1信号通路中医药改善肿瘤免疫抑制微环境研究进展[J]. 中国中医药信息杂志, 2020, 27(2):135-137.
冯高飞, 陈若, 易舒婧等. 试论中医理论指导下的中晚期恶性肿瘤中西医整合治疗[J]. 中华中医药杂志, 2021, 36(03):1489-1492.
Tu M, Xu J. Advances in immunotherapy for gynecological malignancies[J]. Critical Reviews in Oncology/Hematology, 2023, 188:104063.
Basu P, Mahajan M, Patira N, et al. A pilot study to evaluatehome-based screening for the common non-communicablediseases by a dedicated cadre of community health workersin a rural setting in India[J]. BMC Public Health, 2019, 19(1):14-26.
Cao CJ, Dou CY, Lian J. et al. Clinical outcomes and associated factors of radioiodine-131 treatment in differentiatedthyroid cancer with cervical lymph node metastasis[J]. Oncol Lett, 2018, 15(5):8141-8148.
SHARMA H, TAL, CLARK N A. Microbiota andPelvic Inflammatory Disease[J]. Semin Reprod Med, 2014(32):43-49.
吴艳芳, 陈蕾. 八珍汤加味联合放疗治疗中晚期宫颈癌疗效及对患者细胞免疫水平和营养状态的影响[J]. 陕西中医, 2022, 43(08):1052-1055.
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