In recent years, the morbidity and mortality of malignant tumors is increasing, causing serious harm physically and psychologically, but its treatment is still a difficult problem and is the goal that most medical workers hope to overcome.Cancer edema is a common complication of cancer patients, and it affects the patients'normal treatment progress and reduces quality of life of patients.It is a difficult problem in treatment.Modern medicine adopts symptomatic treatment for cancerous edema.There is no special treatment.Traditional Chinese medicine has always played an indispensable role in the development of medicine.It has formed a unique diagnosis and treatment system, which has a mild effect and comprehensive treatment.It has unique advantages in the treatment of this disease.Zhuling Decoction(猪苓汤)comes from, Treatise on Febrile and Miscellaneous Diseases, which is a classic clinical formula.Zhongjing created this recipe to treat blinding of water and heat.With the development of medicine, the application of Zhuling Decoction has become more widespread in the clinic.This article summarized the relevant literature.Combining with the application of the prescription of Zhuling Decoction in the clinic and starting from the clinical effective cases, it showed the effectiveness of Zhuling Decoction in the treatment of cancer edema, and provided a reference for the clinical treatment of this disease.It is confirmed that the efficacy of traditional Chinese medicine in difficult diseases can be expected.