ZHANG Yunling Treats Multiple System Atrophy with Orthostatic Hypotension from the Perspective of Yin and Yang Tonification
1.Graduate School, Beijing University of Chinese Medicine, Beijing, 100029, China
2.China Academy of Chinese Medical Sciences, Xiyuan Hospital Brain disease department, Beijing, 100091, China
DOI:
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SHI Jingzi, LIU Hongxi, LIANG Xiao, et al. ZHANG Yunling Treats Multiple System Atrophy with Orthostatic Hypotension from the Perspective of Yin and Yang Tonification[DB/OL].(2023-03-27)[2023-11-05].http://cccl-tcm.cacm.org.cn/thesisDetails?columnId=35741289&Fpath=home&index=0
DOI:
SHI Jingzi, LIU Hongxi, LIANG Xiao, et al. ZHANG Yunling Treats Multiple System Atrophy with Orthostatic Hypotension from the Perspective of Yin and Yang Tonification[DB/OL].(2023-03-27)[2023-11-05].http://cccl-tcm.cacm.org.cn/thesisDetails?columnId=35741289&Fpath=home&index=0DOI:
ZHANG Yunling Treats Multiple System Atrophy with Orthostatic Hypotension from the Perspective of Yin and Yang Tonification
Summary of case history, The chief complaint of the patient was "dizziness with weakness of both lower limbs and unstable walking for 2 years, aggravated for 8 months". Two years ago, the patient had dizziness with weakness of both lower limbs and unstable walking. In October 2019, he was hospitalized and diagnosed with multiple system atrophy. In August 2020, the patient's symptoms were gradually aggravated, such as unclear speech and urinary incontinence. After re-hospitalization, his condition was still progressive, manifested as dizziness, blurred vision, unstable walking and forward walking,weakness of both lower limbs, unclear speech, urinary incontinence, etc. He had a history of chronic diseases such as hypertension, hyperlipidemia, multiple cerebral infarction and lung cancer after operation. Pale and dark tongue with thin and white coating and deep and thready pulse.,TCM diagnosis, vertigo, false labor syndrome: deficiency of spleen and kidney,deficiency of yin and Yang,Western medicine diagnosis, orthostatic hypotension, multiple system atrophy,Therapeutic methods, Traditional Chinese medicine treatment is based on strengthening the spleen and tonifying the kidney, warming Yang and replenishing yin. Based on the relationship between yin and Yang, the prescription is modified Yougui Pill and Ginseng and Aconiti Praeparatae Decoction. Combined with the patient's medical history, symptoms and signs, it is considered that the patient is more inclined to Yang deficiency, so the modification is slightly focused on replenishing qi and warming Yang, and the modification is based on the patient's symptoms during follow-up. Non-drug therapy is mainly based on limb exercise rehabilitation;The main points of western medicine treatment are to give pramipexole hydrochloride tablets and Butylphthalide to improve symptoms, control underlying diseases, nourish nerves and symptomatic treatment.,Clinical outcomes, The patient's symptoms were improved after taking the medicine at the first visit, and the follow-up treatment was still based on the method of tonifying both yin and Yang, which was modified on the basis of the first visit prescription, and now the quality of life was significantly improved, although the condition was repeated from time to time, but the degree was reduced compared with the previous one.
关键词
多系统萎缩直立性低血压阴阳双补法右归丸参附汤
Keywords
multiple system atrophyorthostatic hypotensionyin and yang tonificationyougui pillginseng and aconiti praeparatae decoction
references
GILMAN S,WENNING GK,LOW PA,et al.Second consensus statement on the diagnosis of multiple system atrophy[J].Neurology,2008,71(9):670-6.
Foubert-SamierAlexandra,Anne Pavy-Le Traon,GuilletFlorian,et al.Disease progression and prognostic factors in multiple system atrophy: a prospective cohort study[J].Neurobiol Dis,2020,139(prepublish):104813.