莲花解毒汤治疗五步蛇咬伤40例临床观察

陈俊; 董德刚; 严张仁; 王万春; 易军; 毛文丽; 李燕芳; 王建刚; 张乃炘; 刘良; 王希

doi:10.3969/j.issn.1006-2157.2020.12.013

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莲花解毒汤治疗五步蛇咬伤40例临床观察

中国中医药临床案例成果库 | 临床研究

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莲花解毒汤治疗五步蛇咬伤40例临床观察
Clinical observation of 40 cases of Agkistrodon acutus bite treated with Lianhua Jiedu Tang
1.江西中医药大学　江西　330004
2.江西中医药大学附属医院
DOI：10.3969/j.issn.1006-2157.2020.12.013

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陈俊, 董德刚, 严张仁, 等. 莲花解毒汤治疗五步蛇咬伤40例临床观察[DB/OL].（2023-09-15）[2023-11-05].http://cccl-tcm.cacm.org.cn/thesisDetails#10.3969/j.issn.1006-2157.2020.12.013

Chen Jun, Dong Degang, Yan Zhangren, et al. Clinical observation of 40 cases of Agkistrodon acutus bite treated with Lianhua Jiedu Tang[DB/OL].（2023-09-15）[2023-11-05].http://cccl-tcm.cacm.org.cn/thesisDetails#10.3969/j.issn.1006-2157.2020.12.013
陈俊, 董德刚, 严张仁, 等. 莲花解毒汤治疗五步蛇咬伤40例临床观察[DB/OL].（2023-09-15）[2023-11-05].http://cccl-tcm.cacm.org.cn/thesisDetails#10.3969/j.issn.1006-2157.2020.12.013 DOI：

Chen Jun, Dong Degang, Yan Zhangren, et al. Clinical observation of 40 cases of Agkistrodon acutus bite treated with Lianhua Jiedu Tang[DB/OL].（2023-09-15）[2023-11-05].http://cccl-tcm.cacm.org.cn/thesisDetails#10.3969/j.issn.1006-2157.2020.12.013 DOI：

摘要

目的,2,对莲花解毒汤治疗五步蛇咬伤进行临床观察。,方法,2,80例五步蛇咬伤患者随机分为对照组与治疗组，每组40例。对照组予西医常规治疗；治疗组在西医常规治疗基础上，予莲花解毒汤口服。治疗1周后，分别记录2组患者平均治愈时间，肿痛瘀消退时间，治疗前、后的局部症状及全身体征总积分及总有效率。,结果,2,治疗组、对照组总有效率分别为87.17%、65.78%。2组患者在平均治愈时间，肿痛瘀消退时间，治疗后第3、7天症状与体征总积分差别有统计学意义。治疗组疗效优于对照组（,P,<,0.05）。,结论,2,莲花解毒汤可有效抑制五步蛇毒活性，疗效确切，值得临床进一步推广。

Abstract

Objective,2,To observe the clinical effect of ,Lianhua Jiedu Tang,(Bearded Scutellaria Toxinremoving Decoction, LHJDT) on ,Agkistrodon acutus, bite.,Methods,2,80 patients bitten by ,Agkistrodon acutus, were randomly divided into control group and treatment group with 40 patients in each group. While the control group was given conventional Western medical treatment, patients in the treatment group took LHJDT orally in addition to the conventional treatment. During one-week treatment, the average recovery time, the time swelling, pain and ecchymosis took to subside, and the total scores of local symptoms and systemic signs of the two groups before and after treatment were measured and recorded; furthermore, the total effective rates of the two groups were compared.,Results,2,The total effective rates were 87.17% and 65.78% in the treatment and control groups respectively. There were significant differences between the two groups of patients in the average recovery time, the time swelling, pain and ecchymosis took to subside, and the total scores of local symptoms and systemic signs on Day 3 and Day 7 during the treatment course. The curative effect of the treatment group was better than that of the control group (,P,<,0.05).,Conclusion,2,LHJDT can inhibit the activity of snake venom of ,Agkistrodon acutus, with definite therapeutic effect, and further clinical application is needed.

关键词

莲花解毒汤五步蛇咬伤局部症状全身体征

Keywords

Lianhua Jiedu Tangagkistrodon acutus bitelocal symptomssystemic signs

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