Sjogren's syndrome-related interstitial lung diseases belong to traditional Chinese medicine "dryness Bi" "lung Bi" "lung impotence" category. Based on the theory of "Pibu-meridians-viscera organs", the paper forms a spatial framework, emphasizes the overall and comprehensive exploration of the hidden places of pathogenic factors, and makes clear the route of transmisson and the actual changes of the disease. The disease is based on positive deficiency, the core pathogenesis is the abnormal transport of Qi and blood in the "Pibu-meridian-viscera" network system, and the block of phlegm and blood stasis is the key pathological product and pathogenic factor. The pathological evolution process is as follows: the skin is affected by pathogenic factors and xuanfu stagnation in the early stage, the distribution of Jingjin and phlegm and blood stasis is lost in the middle stage, and the late stage is characterized by the constant loss of refined deficit and the loss of zang-fu use. The treatment should be based on the disease location, and the main treatment principles should be early dispelling Qi activity, eliminating phlegm and driving blood stasis in the middle stage, and attack and repair in the late stage. The dynamic differentiation and treatment should be performed to cut off the development of the disease, so as to be beneficial to clinical practice.