By discussing and summarizing Professor ZHOU Zhong-ying＇s clinical thinking and experience in treating epilepsy from wind and phlegm, and attaching an introduction of case studies, we hope to provide reference for clinical practice.Professor ZHOU Zhong-ying put forward that the core pathogenesis of epilepsy is"wind-phlegm closure and mental failure"based on many years of practice.The pathogenesis of wind phlegm is characterized by glue hardening, multiple viscera and multiple syndromes.The clinical syndromes are most related to wind, phlegm, fire, blood stasis and deficiency.The therapeutic principle is distinguishing the primary and secondary of deficiency and excess.It is not necessary to absolutely divide the onset period and the rest period.It is emphasized that the deficiency may not be fully replenished when the patient is in the rest period, and the expelling wind and resolving phlegm should be throughout the treatment.Compound prescriptions are often used.This paper also summarizes ZHOU Zhong-ying＇s basic prescriptions for the treatment of epilepsy and the additions and subtractions commonly used, and concretely analyses the medication characteristics.