Objective,2,To observe the clinical efficacy of ZHENG's heat reinforcing needling manipulation in adjunctive treatment of middle-late gastric cancer with deficiency-cold in spleen and stomach syndrome.,Methods,2,Seventy-two cases of middle-late gastric cancer with deficiency-cold in spleen and stomach syndrome were divided into control group and treatment group according to random number table method, with 36 cases in each group. There were 2 drop-out cases in each group, and 34 cases were included in each group finally. The control group was given routine Western medicine treatment, on this basis, the treatment group was given ZHENG's heat reinforcing needling manipulation. Acupuncture treatment was performed once a day, 6 days as 1 course of treatment, rest for 1 day between courses of treatment, totally 2 courses of treatment. The clinical efficacy, the average times of daily pain attacks, analgesia duration, dosage of oxycodone hydrochloride prolonged-release tablets, and incidence of adverse reactions after treatment, along with numerical rating scale(NRS)score, and Karnofsky performance scale(KPS)score before and after treatment were compared between the 2 groups.,Results,2,The total effective rate and incidence of total adverse reactions were 67.6% (23/34) and 52.9% (18/34) in the control group, and 88.2% (30/34) and 29.4% (10/34) in the treatment group, respectively, and the differences were statistically significant between the 2 groups(P<0.05).After treatment, the times of pain attacks and the dosage of oxycodone hydrochloride pro-longed-release tablets in the treatment group significantly reduced, and analgesia duration significantly prolonged, and the differences were statistically significant between the 2 groups(P<0.05).After treatment, NRS scores in both groups decreased significantly, while KPS scores in both groups increased significantly, and the differences were statistically significant compared with those in the same group before treatment(P<0.05), moreover, the improving effect in the treatment group was more significant, and the differences were statistically significant compared with those in the control group after treatment(P<0.05).,Conclusion,2,It has definite clinical efficacy, good analgesic effect, and low adverse reactions to use ZHENG's heat reinforcing needling manipulation in adjunctive treatment of middle-late gastric cancer with deficiency-cold in spleen and stomach syndrome, which deserves clinical promotion and application.