Liver-stomach disharmony is one of themain pathogenesis of functional dyspepsia (FD) . Zhou Zheng-hua has found that there aremany subtypesof liver-stomach disharmony, and the pathogenesis follows the five-step evolution processof＂depression→attacking thoroughfare vessel (TV) →transforming into fire→damaging yin→forming blood stasis＂. In the initial stage, the patho-genesis is stagnation of liver, qi, wood failing to disperse earth. Adhering to the principle of controlling developmentof existing dis-ease, because＂liver diseasesmay affect the function of the spleen, strengthening the spleen is themost important＂. At this stage, Four Gentlemen Decoction can be used to strengthen the spleen and help transport. When the stagnation of liver, qi, develops fur-ther, the disorder of liver, qi, occurs, the dispersing is toomuch, the attack of liver, qi, is too strong, the treatment should focus on reg-ulating, qi, so Frigid Extremities Powder combined with Modified Upper-Lower and Right-Left Decoction can be used. Long-time stagnation of liver, qi, may transform into fire, make, qi, and fire have same disease, so Liver-Resolving Decoction combined with Modified Gallbladder-Warming Decoction can be used. For liver heat and spleen cold syndrome, Bupleurum and Cinnamon Twig and Dried Ginger Decoction can be used towarm cold inmiddle energizer and clear heat in the revertingmeridian. If liver, qi, accu-mulates and transforms into fire, damaging liver, qi, aspect, Yang hyperactivity and excessive fire will burn blood aspect, blood will become thick and fail tomove smoothly, resulting in blocked collaterals, blood stasis, and fire damaging nutrient yin, so the treat-ment is to soften the liver, benefit the stomach, nourish yin and calm themind, and Yin-Nourishing and Two-Ingredient Decoction combined with Modified Jade Lady Decoction can be used. For patientswith FD who have nothealed for a long time but combined with obvious blood stasis, the treatmentmethods are also differentiated according to blood stasis caused by different pathogenesis. Each stage can exist independently or cause disease simultaneously. It is necessary to grasp themain pathogenesis and understand the nature, trend and prognosis of the disease before applying drugs to the syndrome.