Professor CHEN Xiaoning believes that vocal cord leukoplakia is mostly caused by mutual accumulation of phlegm and blood stasis, disharmony of liver and stomach, and qi deficiency and phlegm dampness.Therefore, he uses the following methods in treating the disease: resolving phlegm and eliminating blood stasis, dissipating mass and easing voice, descending adverse qi and harmonizing stomach, benefiting stomach and resolving phlegm, etc.Self-made Huatan Kaiyin Formula(化痰开音方), Shugan Hewei Decoction(疏肝和胃汤), and Buzhong Yiqi Decoction(补中益气汤) combined with Sijunzi Decoction(四君子汤) are the commonly used prescriptions.In choosing drugs, botanical drugs are preferred because its light property helps to reach the lesions of the throat, while fierce drugs with severe bitterness and cold are avoid for consolidating spleen and stomach.With flexible diagnosis and treatment based on syndrome differentiation, Professor CHEN stresses the importance of refined prescriptions, mild drugs, small dosage, and postoperative care, which has achieved good curative efficacy.