Prof. MI Jie believes that hepatitis B virus-associated glomerulonephritis (HBV-GN) belongs to deficient root and excessive branch. Kidney deficiency caused by insufficient innate endowment failing in qi transformation leads to acquired malnutrition and failure of transportation of the deficient spleen and stomach. The excessive branch is based on dampness-heat, combined with stasis-toxin. Insufficient healthy qi and excessive pathogenic qi, the struggle between healthy qi and pathogenic qi leads to the body's low resistance to pathogenic qi, excessive pathogenic qi and deficient healthy qi. Excess causes deficiency and deficiency-excess in complexity. Most of the diseases are caused by dampness-heat and stasis-toxin, which affects the entire course of the disease, involving three zang-organs of the liver, spleen and kidney, such as stagnated heat in liver meridian, spleen deficiency with dampness retention, failure of kidney storing essence. Over time, the liver, spleen, kidney, qi, blood, yin and yang are all deficient, the lingering dampness, heat and stasis consume the healthy qi continuously leading to more deficient conditions which is difficult to be cured. In terms of treatment, reinforcing healthy qi to eliminate pathogenic factors is the main treatment principle. Clearing away heat, eliminating dampness, activating blood, resolving stasis and detoxifying are the main treatment methods. Treating the branch and the root simultaneously. Yinchen Chixiaodou Decoction is the main prescription, using syndrome differentiation and treatment, adding and subtracting according to symptoms with good effects.