With the acceleration of life rhythm as well as the pressure from work, study, life and other aspects, the anxietyhas been increased and there is an increase in the number of people with generalized anxiety disorder. Generalized anxiety disorder is a psychosomatic disease. In addition to mental symptoms, it often involves multiple systems such as nerves, breathing, digestionand circulation. The clinical symptoms are complex. Although Western medicine has a definite curative effect and rapid onset of the disease, there are drawbacks such as addiction, drug resistance, single drug target, multiple adverse reactions and poor patient compliance. In comparison, traditional Chinese medicine compound has the advantages of multiple ingredients, multiple targets, good clinical efficacy and few adverse reactions. It can be treated on the basis of syndrome differentiation and treatment for individual differences. Director LIU Xinchun believes that emotional distress, excessive worry, stagnation of Qi, liver Qi depression, disharmony between spleen and stomach, phlegm, blood stasis and internal firedisturbing the mind, the restless mindare the main pathogenesis of generalized anxiety disorder for the young and middle-aged. In clinical treatment, it is recommended to soothe liver and regulate Qi and adjust the spleen and stomach as the basic treatment method, supplemented with calming the mind, combined with resolving phlegm, eliminating blood stasis and clearing fire methods and psychological therapy. Multiple methods are used together. ,Chaihu Shugan, Powder and ,Wendan, Decoction are classic prescriptions of traditional Chinese medicine. Director LIU Xinchun added or subtracted the self-made prescription on this basis. The clinical treatment of young and middle-aged patients with generalized anxiety disorder is satisfactory, and 2 typical cases were attached to provide some ideas and methods for clinical prevention and treatment.