Flatulence and endogenous heat is the core pathogenesis of spleen heat diseases. Due to the differences in constitution and living environment, the main manifestations of it also vary, but the fundamental cause is believed to be eating too much fat and sweet food. To much fat food makes heat evils enter into and accumulate in the interior, while sweet food leads to abdominal fullness and distention over time. On the basis of flatulence, internal heat is metamorphosed, which is manifested as a kind of fire heat, such as damp heat, liver heat, etc., resulting in liver qi to invade the stomach, spreading to the liver, forming liver heat and blood tier, causing blood heat, fire and qi stagnating, thereby causing liver heat, blood heat, and damp heat to accumulate and bind in the interior. Or if the spleen is weak, liver qi may stagnate and bind, which affects the drainage of liver qi, causing the spleen to fail in transportation and transformation, aggravating flatulence and the stagnant liver qi transforming into fire over time, forming internal heat and spreading to the viscera, resulting in liver heat, blood heat, and damp heat to bind and to be intermingled with each other. Clinically, Academician Tong Xiaolin usually uses peony root, unprocessed rehmannia root and golden thread to make up a three-element prescription for "clearing away the intermingled liver heat, blood heat and damp heat" . Combining different disease backgrounds and conditions, Academician Tong Xiaoli usually adds or subtracts the dosages flexibly and accurately, with a result of a good curative effect.