According to Professor TONG Xiaolin, accumulated damp-heat and wind-evil in the skin is thought to be the main pathogenesis of diabetes mellitus complicated with pruritus, which is often treated by clearing heat and dampness, dispelling wind-evil and relieving itching. Sophorae Flavescentis, cortex dictamni and Fructus Kochiae are commonly used in clinical treatment of diabetes which is in a stage of heat evil thriving combined with pruritus. In the prescription, Sophorae Flavescentis has the effect of clearing heat and drying dampness, and the commonly dosage is 6-15 g; Cortex Dictamni is used for clearing heat, drying dampness and dispelling the wind and the dosage is 9-30 g; Fructus Kochiae plays the role of heat-clearing, damp-inhibiting and wind-dispersing, and the commonly dosage is 15-30 g. They often compatibles with Scutellaria baicalensis, Coptis chinensis when damp-heat is more serious, and compatibles with Coix seed, Poria cocos, dried tangerine or orange peel when damp evil is relatively serious.