This paper analyzed the clinical experience of Professor LAI Xinsheng in treating sequelae of neuralgia caused by herpes zoster based on syndrome differentiation with, tong yuan, therapy(通元疗法). Professor LAI believed that the incidence of herpes zoster was mostly caused by weak healthy, qi, damage by wind-heat toxicity;or liver depression transforming into fire, and accumulation of fire toxicity;or wind-cold accumulation and block in body. The location of this disease was in the liver and lung, subsequently in the kidney for a long time. Clinical manifestations are mixed wind-heat toxicity, but mainly in wind-heat;mixed wind-heat toxicity, but mainly in toxicity;stagnation of wind-cold. Acupuncture therapy of purging heat and regulating the liver, oral administration of Chinese medicine therapy, Chaizhang Jiedu Decoction,(柴杖解毒汤), external washing therapy, Langen Lotion,(蓝根洗剂)were self-designed. Combined with zang-fu and meridian differentiation, ",Tong yuan, Therapy" was used to treat from primordial spirit with acupuncture and Chinese medicine to tranquilize the spirit and regulate yin and yang.