Henoch-Schonlein purpura nephritis is one of the most common secondary glomerular diseases in pediatrics.Traditional Chinese medicine has unique advantages in the prevention and treatment of Henoch-Schonlein purpura nephritis in children.Professor YAN Huimin has been engaged in clinical research of children's HSPN for more than 30 years and has accumulated rich experience.Based on the theory of collateral disease, she explains the etiology and pathogenesis of HSPN, and thought that the etiology of it is not external but internal.The pathogenesis of the acute stage is mainly the accumulation of damp and heat, which damages the kidney collaterals.With the prolongation of the course of the disease, internal and external evils block the kidney collaterals and burn the Yin collaterals for a long time.Therefore, Professor YAN emphasizes the treatment of the disease by stages and differentiation of syndromes.The treatment of the disease should be based on "dredging", and the principle of "activating collaterals and removing blood stasis" throughout the treatment of the disease.In the acute stage, she uses the methods of removing dampness and toxin, promoting blood circulation and removing blood stasis, and the treatment mainly focuses on nourishing Yin and Qi, removing blood stasis and removing dampness.The main traditional Chinese medicines are Fengweicao(,Pteris multifida, Poir), Daokoucao(,Achyranthes aspera, L), Kushen(,Sophora flavescens,), Shiwei(,Pyrrosia lingua,), Yiyiren(,Coix lacrymajobi,), Baijiangcao(,Patrinia,), Lianqiao(,Forsythia suspensa,), Chixiaodou(,Vigna umbellata,), Puhuangtan(,Typha angustifolia charcoal,), Lianxu(,Nelumbo nucifera Gaertn,.), Douchi(fermented soya beans), Shanyao(,Dioscorea oppositifolia,), Qianshi(,Euryale ferox,), etc.Professor YAN has achieved good clinical effect according to the addition and subtraction of different syndromes of children with Henoch-Schonlein purpura nephritis.