According to many years of clinical experience, Prof.SHENG believes that purpura nephritis in children is located in the kidney and bladder.The disease belongs to the excessive patholgical sydnrome(or excessive and deficiency mixed sydnrome). Intrinsic damp and phlegm-inducing collaterals are the main pathogenesis. "Damp and heat" and "blood stasis" are the basic pathological factors.Therapeutic treatment is based on different types of etiology and pathogenesis combined with blood circulation.This article mainly starts from the etiology and pathogenesis, syndrome differentiation, rule, prescription selection and other aspects, combined with typical cases, and introduces Professor SHENG Lixian's experience in the treatment of purpura nephritis in children to provide some ideas and methods for the treatment of the disease by clinical Chinese medicine.