从三阴寒化论治皮痹案
Treatment of Systemic Sclerosis from Taiyin, Shaoyin and Jueyin Cold Transformation
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1.云南中医药大学第一临床医学院,昆明 650000
2.云南中医药大学第一附属医院风湿病科,昆明 650000
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刘念,刘维超,晏蔚田,等.从三阴寒化论治皮痹案[DB/OL].(2023-12-26)[2023-12-26].https://cccl-tcm.cacm.org.cn/thesisDetails?columnId=46791928&Fpath=home&index=0&lang=zh
LIU Nian,LIU WeiChao,YAN WeiTian,et al.Treatment of Systemic Sclerosis from Taiyin, Shaoyin and Jueyin Cold Transformation[J].,
刘念,刘维超,晏蔚田,等.从三阴寒化论治皮痹案[DB/OL].(2023-12-26)[2023-12-26].https://cccl-tcm.cacm.org.cn/thesisDetails?columnId=46791928&Fpath=home&index=0&lang=zh DOI:
LIU Nian,LIU WeiChao,YAN WeiTian,et al.Treatment of Systemic Sclerosis from Taiyin, Shaoyin and Jueyin Cold Transformation[J]., DOI:.
病史摘要,2,以“双手皮肤变硬半年伴左手食指末端破溃1月”为主诉。患者6年确诊为类风湿关节炎,不规律服用甲氨蝶呤片及叶酸片。2022年08月双手皮肤逐渐发硬、活动不利,遇寒触冷时手指雷诺现象,得暖可自行缓解。2023年02月左手食指远端指间关节发黑、萎缩、破溃、感觉减退,当地医院予甲硝唑注射液、丹参注射液输液治疗,症状无改善。2023年3月16日左手食指远端指间关节部分组织脱落。就诊时症见:双手指肿胀,皮肤发硬,色紫暗,肤温低,遇寒触冷雷诺现象。左手食指末端指节发黑、萎缩,部分破溃缺如,无渗出。四肢多关节疼痛,遇寒加重得温可缓。神疲乏力、脘腹胀闷、纳呆、眼周青,小便清长,大便稀溏2~3日1行。舌淡暗泛青,苔白腻,脉沉紧尺弱。中医诊断 皮痹(水寒土湿木郁证)西医诊断 重叠综合征(系统性硬化症、类风湿关节炎);继发性肺间质纤维化;轻度肺动脉高压;高凝状态;三尖瓣关闭不全;高胆固醇血症;亚临床甲减干预措施 中医予中药内服治疗为主(附子桂枝汤、当归四逆汤、潜阳封髓丹、补中桂枝汤)。西医予抑制免疫、抗炎症痛、抗纤维化、抗凝、扩血管,及补钙、抑酸护胃等对症治疗。疗效转归 好转。
Summary of case history, The main complaint was "the skin of both hands became hard for half a year with the end of the left index finger broken for 1 month". The patient was diagnosed with rheumatoid arthritis 6 years ago and took methotrexate tablets and folic acid tablets irregularly. In August 2022, the elasticity of the skin of both hands gradually decreased and the activity was unfavorable, the raynaud phenomenon when it was cold could , and alleviate when it was warm. In February 2023, the distal interphalangeal joint of the left index finger was black, atrophy, ulceration, and decreased sensation. Metronidazole injection and salviorrhiza injection were treated in the local hospital, but the symptoms did not improve. 16/03/2023, partial tissue loss of distal interphalangeal joint of left index finger. Symptoms: swollen hands, hard skin, dark purple color, low skin temperature. The end knuckles of the left index finger were black, atrophied, partially broken and absent, without oozing. Multiple joint pain in the limbs, pain aggravate the temperature was cold. Fatigue, abdominal distension, dull, the color around the eyes is green, urine clear and long, loose stool 2-3 days once. Tongue color is light, dark, green, white and greasy fur, pulse is heavy and weak.,TCM diagnosis, bi syndrome of skin (cold dampness stays in the spleen,kidney, liver, and cold dampness is difficult on the body surface),Western medicine diagnosis, overlap syndrome (systemic sclerosis, rheumatoid arthritis),;secondary pulmonary interstitial fibrosis,;mild pulmonary hypertension,;hypercoagulability,;tricuspid valve insufficiency,;hypercholesterolemia,;subclinical hypothyroidism.,Therapeutic methods, The TCM treatment is oral TCM decoction (Fuzi Guizhi Decoction, Angelica Sini Decoction, Qianyang Fengbei Dan, Buzhong Guizhi Decoction). The Western medicine gives symptomatic treatment such as immune suppression, anti-inflammatory pain, anti-fibrosis, anticoagulation, vasodilation, calcium supplement, acid inhibition and stomach protection.,Clinical outcomes, remission
皮痹重叠综合征系统性硬化症扶阳
Bi syndrome of skinOverlapping syndromeSystemic sclerosisstrengthening yang-qi
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