Summary of case history,　The patient, female, 84 years old, was admitted to the hospital on May 20, 2023, with the chief complaint of "runny nose and cough for 2 days, fever for 1 day". After admission, she had fever, cough and sputum, low blood oxygen saturation, and was given endotracheal intubation and ventilation. T 38.7℃, P 108 beats/min, R 28 breaths/min, BP 114/62mmHg, SpO2 87%. Coarse breath sounds in both lungs, moist rales in both lower lungs. The abdomen was soft, with mild tenderness in the lower abdomen, no rebound pain in the whole abdomen, and no mass was palpated. Bowel sounds were 4 times/min. No other abnormalities. The tongue was thin and red with thin yellow coating, and the pulse was deep and stringy. May 20, 2023: Chest CT: bilateral lung infection; CBC+CRP: WBC 18.73×10,9,/L, NE% 93.1%, CRP 102.35mg/L, HGB150g/L, PLT 194×10,9,/L. Novel coronavirus antigen test: positive.,TCM diagnosis,　epidemic disease dyspnea qi and yin deficiency, phlegm-heat obstructing the lungs,Western medicine diagnosis,　severe pneumonia ;acute respiratory distress syndrome type I respiratory failure ;sepsis ;novel coronavirus infection ;coronary atherosclerotic heart disease acute myocardial injury heart function class IV (NYHA classification);hypertension grade 3 very high risk group ;type 2 diabetes,Therapeutic methods,　Anti-infection: Paxlovid antiviral, piperacillin sodium and tazobactam sodium combined with moxifloxacin hydrochloride anti-infection, later upgraded antibiotics meropenem combined with moxifloxacin anti-infection. Oxygen therapy: nasal cannula oxygen inhalation-face mask oxygen inhalation-non-invasive ventilator (May 22)-endotracheal intubation invasive mechanical ventilation (May 26). Enoxaparin anticoagulation; given regular insulin pump to regulate blood glucose; high lateral position ventilation; nocturnal sedation and analgesia, daytime awakening. Traditional Chinese medicine mainly clear heat and nourished qi and yin, and also clear heat and drained pus, using modified Qianjin Weijing Decoction.,Clinical outcomes,　The first stage was general ward treatment (8 days): The general treatment was anti-infection, traditional Chinese medicine to nourish qi and yin, clear lung detoxification and phlegm treatment, the patient had a lot of sputum, the infection gradually worsened, and was transferred to ICU. The second stage was ICU treatment (23 days): ventilator-assisted ventilation (12 days), extubation and weaning, infection gradually improved, functional exercise, discharged after improvement.