Summary of case history,　Miss Li was admitted to the hospital for "recurrent polyarticular pain with skin itching for 2+ years, aggravated with shortness of breath for half a year". 2+ years ago, the patient had pain in both shoulders, elbows, wrists, metacarpals, proximal interphalangeal joints, knees and ankles, accompanied by itching of the skin, dry mouth and eyes, and his hands were characterized by mechanics' hands and weenie-like changes, which the patient did not pay attention to and was systematically treated. and systematic diagnosis and treatment. Half a year ago (December 2022), without obvious triggers to sense the aggravation of episodic symptoms, to the right hip, right knee pain, skin roughness, accompanied by shortness of breath, aggravated by activity, claudication, consultation in the local hospitals did not see any relief and then referred to our hospital.,TCM diagnosis,　Skin impediment-syndrome of paralysis by cold and dampness,Western medicine diagnosis,　Systemic sclerosis with interstitial lung disease,Therapeutic methods,　Traditional Chinese medicine gives Duhu parasitic soup plus reduction to dispel wind and cold, remove dampness and pass the collaterals, with our "cold paralysis soup" external use to enhance the therapeutic effect; Western medicine gives anti-inflammatory, regulating immunity, anti-pulmonary fibrosis, expanding blood vessels, gastric protection, calcium supplementation, and improve the sclerosis of the skin as the main focus.,Clinical outcomes,　Multi-joint pain significantly improved, skin itching significantly relieved, dry mouth, dry eyes better than before, hands waxing and waning, rough skin of both hands, swelling of both hands significantly reduced, disappearance of dermatoglyphics, no significant wheezing, sleep is possible, tongue pale, moss white, pulse slightly tight.