Summary of case history,　This disease was caused by clonorchiasis, resulting in subacute liver failure and complications of hepatic encephalopathy. The condition was critical. In Western medicine, comprehensive treatments such as general supportive treatment, symptomatic treatment, etiology treatment, complication treatment, and artificial liver support treatment were administered. In traditional Chinese medicine, based on the theory of "toxic pathogen-toxic turbidity pathogenesis" of liver failure, the "truncated reversal" method was applied using a combination of JIE DU HUA YU decoction and GAN LU XIAO DU pill for detoxification and removal of blood stasis, along with diuresis and resuscitation promotion. For hepatic encephalopathy, the "purgation and resuscitation" method was adopted, and traditional Chinese medicine characteristic therapy of retention enema with rhubarb decoction was used. Timely multidisciplinary collaborative diagnosis and treatment were executed to address acute cholangitis induced by insect repellent therapy, with ERCP yellow reduction treatment performed while clarifying the nature of the bile duct space-occupying lesion. Traditional Chinese medicine focused on clearing heat and promoting fluid production, tailoring treatments according to syndromes and signs, treating both symptoms and underlying causes. This collaborative approach led to a favorable prognosis, highlighting the advantages of multidisciplinary and coordinated treatment for acute jaundice with traditional Chinese and Western medicine.,TCM diagnosis,　Jaundice—Acute Jaundice (Syndrome of excessive epidemic virus).,Western medicine diagnosis,　1. Mid stage of subacute liver failure, Clonorchiasis sinensis; 2. Hepatic Encephalopathy (Type A HE2).,Therapeutic methods,　In Western medicine, comprehensive treatments such as general supportive treatment, symptomatic treatment, etiology treatment, complication treatment, and artificial liver support treatment were administered; In traditional Chinese medicine, based on the theory of "toxic pathogen-toxic turbidity pathogenesis" of liver failure, the "truncated reversal" method was was applied using a combination of JIE DU HUA YU decoction and GAN LU XIAO DU pill for detoxification and removal of blood stasis, along with diuresis and resuscitation promotion. For hepatic encephalopathy, the "purgation and resuscitation" method was adopted, and traditional Chinese medicine characteristic therapy of retention enema with rhubarb decoction was used. Timely multidisciplinary collaborative diagnosis and treatment were executed to address acute cholangitis induced by insect repellent therapy, with ERCP yellow reduction treatment performed while clarifying the nature of the bile duct space-occupying lesion. Traditional Chinese medicine provided the function of clearing heat and promoting fluid production, and the treatments followed by syndromes and signs.,Clinical outcomes,　The patient achieved clinical cure with a favorable prognosis.