中医治疗类风湿关节炎合并肺孢子菌肺炎患者1例
A Case of Rheumatoid Arthritis Complicated With Pneumocystis Pneumonia Treated by Traditional Chinese Medicine
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1.重庆市中医院风湿免疫科,重庆 400021
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王淼,朱丰林,张莹,等.中医治疗类风湿关节炎合并肺孢子菌肺炎患者1例[DB/OL].(2023-11-13)[2023-11-13].http://cccl-tcm.cacm.org.cn/thesisDetails?columnId=43867580&Fpath=home&index=0&lang=zh
WANG Miao,ZHU Fenglin,ZHANG Yin,et al.A Case of Rheumatoid Arthritis Complicated With Pneumocystis Pneumonia Treated by Traditional Chinese Medicine[J].,
王淼,朱丰林,张莹,等.中医治疗类风湿关节炎合并肺孢子菌肺炎患者1例[DB/OL].(2023-11-13)[2023-11-13].http://cccl-tcm.cacm.org.cn/thesisDetails?columnId=43867580&Fpath=home&index=0&lang=zh DOI:
WANG Miao,ZHU Fenglin,ZHANG Yin,et al.A Case of Rheumatoid Arthritis Complicated With Pneumocystis Pneumonia Treated by Traditional Chinese Medicine[J]., DOI:.
病史摘要,2,患者,女,66岁,主因“多关节肿痛1年,伴咳嗽咳痰10天”入院。1年前因多关节肿痛,于外院诊断“类风湿关节炎”。入院前3月开始服用“甲氨喋呤、来氟米特、雷公藤”抑制免疫,病情稳定。10天前因受凉出现咳嗽、咳大量黄白粘痰。既往病史:磺胺类药物过敏。入院症见:咳嗽、咳大量黄白粘痰,胸闷,乏力,不欲饮食,口干口苦,大便时干时稀,舌淡红,苔白腻,右脉滑实,左脉弦。入院查胸部CT提示双肺片絮状模糊影,边界不清;肺泡灌洗液NGS检测:卡氏肺孢子菌阳性。中医诊断 咳嗽(痰湿蕴肺兼肝脾不和证)。西医诊断 卡氏肺孢子菌肺炎、类风湿关节炎、间质性肺炎。干预措施 患者磺胺过敏,且拒绝卡泊芬净等治疗,中医先后予以三子养亲汤、小柴胡汤、黄芪鳖甲汤加减。疗效转归 经4诊后,患者咳嗽、咳痰等症状明显改善,出院2周后复查胸部CT提示双肺云絮状模糊影吸收。
Summary of case history, The patient, a 66-year-old woman, was admitted to the hospital mainly due to "multi-joint swelling and pain for 1 year, with coughing and coughing up a lot of sputum for 10 days". One year ago, the patient was diagnosed with "rheumatoid arthritis" at another hospital due to multiple joint swelling and pain. 3 months ago, she began to take "methotrexate, leflunomide, triptovine" to suppress immunity, and her condition was stable. 10 days ago, the patient caught a cold, with coughing and coughing up a lot of sputum. Past medical history: sulfonamide allergy. Admission symptoms include: cough, cough up a lot of yellow and white sticky sputum, chest tightness, fatigue, lack of desire to eat, dry mouth and bitter mouth, stool is sometimes dry, sometimes loose, pale red tongue, white and greasy, smooth right vein, and chord left vein. Chest CT showed flocculent blur and unclear borders of both lung films. NGS test of alveolar lavage fluid: positive for Pneumocystis carinii.,TCM diagnosis, Syndrome of phlegm-dampness accumulation of lung and Disharmony between liver and spleen.,Western medicine diagnosis, Pneumocystis pneumonia, rheumatoid arthritis, interstitial pneumonia.,Therapeutic methods, Because the patient is allergic to sulfonamides, we cannot use sulfonamide anti-infective therapy. And the patient refuses treatment such as caspofungin. Traditional Chinese medicine has successively given Sanzi Yangqin Decoction, Xiaochai Hu Decoction, and Huangqi Biejia Decoction.,Clinical outcomes, After 4 times of diagnosis and treatment, the patient's symptoms such as cough and sputum production were significantly improved. Repeat chest CT 2 weeks after discharge, the results showed that the flocculent blur in both lungs was not significant.
卡氏肺孢子菌肺炎类风湿关节炎中药
pneumocystis pneumoniarheumatoid arthritistraditional Chinese medicine
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