Change Mou, a middle-aged male, had multiple red macules on both upper arms without any inducement two years ago, which caused itching and discomfort. She received symptomatic treatment such as anti allergic treatment in the local hospital. The effect was poor, the itching was aggravated, and the rash on the back, buttocks and perineum gradually appeared, which seriously affected the quality of life. She went to the Hospital of BeiJing and diagnosed "severe specific dermatitis", and was injected with Duprizumab, which still had a poor effect. The patient suffered from itching skin rash, multiple skin scratches and poor sleep, which seriously affected the quality of life. So come to our department for treatment. The main symptoms are: large red rash on both upper arms, back, buttocks, a little clear liquid oozing from buttocks, skin folds thickening, itching, scratches and scaling, listlessness,insomnia, normal urination, and sticky stool. The tongue is dark red, the fur is white and greasy, and the pulse is heavy and slippery.,Summary of case history,　He had a history of type 2 diabetes for 6 years. At present, he has been given insulin to reduce blood sugar. He has no other medical history. He was allergic to wind or pollen in childhood.,TCM diagnosis,　eczema,dampness and toxin is stored inside,Western medicine diagnosis,　severe atopic dermatitis,Therapeutic methods,　I took oral Chinese medicine with the method of ascending clear-qi and descending the turbid, adjusted the pivot of the ascending and descending of the central energizer, opened the skin orifices, and came back five days later to adjust the prescription. In addition, I washed the local area with the external washing prescription of Chinese medicine. The treatment lasted for two week and the total course of treatment was 19 days.,Clinical outcomes,　After the initial diagnosis, the patient's spirit improved, the itching symptoms improved, and the local exudation decreased. After the follow-up visit, fine tune the prescription and add the external washing prescription of traditional Chinese medicine. The patient recovered in two week and did not relapse in two months.