Summary of case history,　The patient with vulgaris pemphigus for 2 years was mainly characterized by erythema, erosion with itch and pain as the main symptoms. During the disease, she had high fever and red eyes. She had been diagnosed as vulgaris pemphigus in many large west hospitals and been treated by corticosteroid and immunosuppressor. Because she couldn't tolerate the side effects of long-term high-dose corticosteroid and immunosuppressor, she wished to be treated in traditional Chinese medicine (TCM ) by professor ZHANG Xijian. The pulse of patient was deep and powerful, heavy pressure-resistant, small slippery, left inch small air mass, small stick floating, right inch gas gathering, floating. The tongue was yellow greasy moss, red tongue.,TCM diagnosis,　Vulgaris pemphigus internal chronic damp toxin, upper fire toxin.,Western medicine diagnosis,　Cholecystitis.,Therapeutic methods,　Oral administration of traditional Chinese medicine decoction for 2 months,.Clinical outcomes,　The patient ' s condition improved obviously and the skin lesion disappeared basically.