杨中中药治疗甲磺酸伊马替尼所致银屑病1例
A Case of Psoriasis Caused by Imatinib Mesylate Treated with Chinese Medicine by YANG Zhong
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1.首都医科大学附属北京中医医院肿瘤科,北京100010
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程培育,杨中.杨中中药治疗甲磺酸伊马替尼所致银屑病1例[DB/OL].(2023-11-10)[2023-11-10].https://cccl-tcm.cacm.org.cn/thesisDetails?columnId=43820661&Fpath=home&index=0&lang=zh
CHENG Peiyu,YANG Zhong.A Case of Psoriasis Caused by Imatinib Mesylate Treated with Chinese Medicine by YANG Zhong[J].,
程培育,杨中.杨中中药治疗甲磺酸伊马替尼所致银屑病1例[DB/OL].(2023-11-10)[2023-11-10].https://cccl-tcm.cacm.org.cn/thesisDetails?columnId=43820661&Fpath=home&index=0&lang=zh DOI:
CHENG Peiyu,YANG Zhong.A Case of Psoriasis Caused by Imatinib Mesylate Treated with Chinese Medicine by YANG Zhong[J]., DOI:.
病史摘要,2,患者老年男性,2016年1月因腹部肿物于外院行胃肠道肿物切除+肝部分切除+胆囊切除术(具体不详),术后病理诊断为胃间质瘤,2018年5月9日因肿瘤复发于北京中医医院行“胃病损切除术+肝病损切除术+腹腔粘连松解术”,术后病理依然是间质瘤,2019年3月患者开始口服甲磺酸伊马替尼,复查腹部增强CT提示腹部占位较前减小,考虑有效,但患者出现双下肢可凹性水肿,胸腹及四肢躯干出现红色皮疹,瘙痒伴脱屑,症状逐渐加重,外院皮肤科诊断为“寻常型银屑病”,患者为求中西医结合治疗就诊北京中医医院门诊,杨中教授四诊合参,认为患者乃脾肾阳虚为本,湿、热、瘀、毒为标,以健脾补肾、清热利湿、活血解毒为治疗大法,患者中药口服期间患者未停服甲磺酸伊马替尼,中西医结合治疗下,患者肿瘤病情稳定,银屑病也得以痊愈。中医诊断 癥瘕,白疕。西医诊断 胃肠间质瘤术后Ⅳ期,局部复发,肝被膜受侵。干预措施 中药汤剂口服。疗效转归 皮疹明显消退,疗效显著,随访病情稳定。
Summary of case history, The patient was an elderly male who underwent gastrectomy+partial hepatectomy+cholecystectomy (details unknown) in January 2016 due to an abdominal tumor in an external hospital. The pathological diagnosis was gastric stromal tumor after surgery. On May 9, 2018, he underwent "gastrectomy+hepatectomy+abdominal adhesion release" in ,Beijing Hospital of Traditional Chinese Medicine, due to tumor recurrence. Postoperative pathology: gastrointestinal stromal tumor. In March 2019, the patient began to take imatinib mesylate orally, The reexamination of abdominal enhanced CT showed that the abdominal space occupation was smaller than before, which was considered effective, but the patient had concave edema of both lower limbs, red rash on chest, abdomen and limbs and trunk, pruritus with scaling, and the symptoms gradually worsened. The dermatology department of the external hospital diagnosed "psoriasis vulgaris", and visited ,Beijing Hospital of Traditional Chinese Medicine, of outpatient department for the treatment of integrated traditional Chinese and western medicine, professor YANG zhong use comprehensive analysis of data gained by four diagnostic methods, thought is the spleen in patients with kidney Yang deficiency and dampness, heat, blood stasis and toxin as standard, with spleen and kidney, clear heat lishi, invigorate the circulation of detoxification treatment. During the oral administration of traditional Chinese medicine, the patient did not stop taking imatinib mesylate, and the patient's tumor condition was stable and psoriasis was cured.,TCM diagnosis, Zheng Jia, Bai Bi,Western medicine diagnosis, Postoperative gastrointestinal stromal tumor stage Ⅳ, local recurrence, hepatic capsule invasion.,Therapeutic methods, Oral Chinese medicine decoction,Clinical outcomes, rash subsided obviously, the curative effect was significant, and the condition was stable during follow-up.
甲磺酸伊马替尼中药银屑病药物不良反应
imatinib mesylatetraditional Chinese medicinepsoriasisadverse drug reactions
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