Summary of case history,　The 34-year-old patient went to the doctor for menopause for more than 5 months, no contraception and no pregnancy again for 4 years after induced abortion. After menarche, the menstrual period and volume were normal, and the abdominal pain is severe upon menstruation. On December 23, 2011, the "chocolate cyst removal of the right ovary" was performed by laparoscopy. After the operation, "Triptorelin Acetate" was injected three times. After three months of menopause, menstruation resumed as before. She was pregnant in February 2013 and has not been pregnant since she underwent "painless abortion" due to work. In the past 2 years, the menstruation has been gradually prolonged, with a menstrual period of 2-3 months usually. The menstrual volume was not stable, the color was dark red, there was no blood clot, and there was slight abdominal pain. She had taken "Climen" for 3 months, and menstruation was available, but the volume was small. The menstruation stopped when she stopped taking the medicine. Sexhormone on March 27, 2016: FSH 63.20 mIU/mL↑, LH 57.91 mIU/mL↑, E2 154.70 pg/mL↓, P 0.78 ng/mL↓; Sexhormone on August 22, 2016: FSH 46.13 mIU/mL↑, LH 15.76 mIU/mL↑, E2 27.39 pg/mL↓, P 0.65 ng/mL. The last menstruation occurred on October 10, 2016, during which she took little food, with easy waking up and poor sleep, obvious drying and sweating at night, low spirit, especially waist pain, no leucorrhea, dry in vagina, and easy defecation and urination. The tongue is ruddy, the fur is thin and white, and the pulse is thin and smooth.,TCM diagnosis,　amenorrhea; infertility (liver depression and spleen deficiency, dysfunction of chong and ren channels, kidney essence deficiency).,Western medicine diagnosis,　premature ovarian insufficiency ;secondary infertility,Therapeutic methods,　It was proposed to adopt the dredging and conditioning method, and apply the Ziteng Siwu Wuzi Decoction.,Clinical outcomes,　Due to busy work and husband's business trip abroad, she did not see a doctor later. On May 26, 2018, she came for a cold and said that her menstruation was normal and she was not pregnant.