胡晓梅教授复方青黄散为主治疗骨髓增生异常综合征伴原始细胞增多(MDS,EB-1)验案1例
A Case of Myelodysplastic Syndrome with Primitive Cellular Hyperplasia (MDS, EB-1) Treated by Prof. HuXiaomei with Compound QingHuangSan
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1.中国中医科学院西苑医院血液科,北京 100091
2.中国中医科学院研究生院,北京100700
3.北京中医药大学 西苑临床医学院,北京 100029
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宋英, 王雪莹, 胡晓梅. 胡晓梅教授复方青黄散为主治疗骨髓增生异常综合征伴原始细胞增多(MDS,EB-1)验案1例[DB/OL].(2023-09-06)[2023-11-05].http://cccl-tcm.cacm.org.cn/thesisDetails?columnId=41363599&Fpath=home&index=0
SONG Ying, WANG Xueying, HU Xiaomei. A Case of Myelodysplastic Syndrome with Primitive Cellular Hyperplasia (MDS, EB-1) Treated by Prof. HuXiaomei with Compound QingHuangSan[DB/OL].(2023-09-06)[2023-11-05].http://cccl-tcm.cacm.org.cn/thesisDetails?columnId=41363599&Fpath=home&index=0
宋英, 王雪莹, 胡晓梅. 胡晓梅教授复方青黄散为主治疗骨髓增生异常综合征伴原始细胞增多(MDS,EB-1)验案1例[DB/OL].(2023-09-06)[2023-11-05].http://cccl-tcm.cacm.org.cn/thesisDetails?columnId=41363599&Fpath=home&index=0 DOI:
SONG Ying, WANG Xueying, HU Xiaomei. A Case of Myelodysplastic Syndrome with Primitive Cellular Hyperplasia (MDS, EB-1) Treated by Prof. HuXiaomei with Compound QingHuangSan[DB/OL].(2023-09-06)[2023-11-05].http://cccl-tcm.cacm.org.cn/thesisDetails?columnId=41363599&Fpath=home&index=0 DOI:
病史摘要,2,患者老年男性,主因“诊断MDS8年,乏力加重1周”就诊,2014年开始给予复方青黄散(3粒/次,Tid)+健脾补肾中药汤剂(六味地黄丸+香砂六君子汤)+小剂量雄激素口服治疗,维持治疗一度血液学改善。2020年初至2020年8月未系统服药治疗,疾病进展。刻下症:乏力,头晕耳鸣,心悸,纳差,夜尿频,大便正常,口中淡,舌淡,苔滑而色白,舌根微黄腻。脉沉细。中医诊断 髓毒劳,脾肾两虚、毒瘀阻滞。西医诊断 骨髓增生异常综合征伴原始细胞增多(MDS,EB-1)。干预措施 复方青黄散(3粒/次,Tid)+健脾补肾中药汤剂(六味地黄丸+香砂六君子汤)+小剂量雄激素口服治疗疗效转归 乏力,头晕耳鸣,心悸等不适症侯消退; 6个月时血液学改善,12个月时完全缓解。
Summary of casehistory, The patient, an elderly male, was diagnosed with MDS for 8 years and his weakness worsened for 1 week. In 2014, he was given compound QingHuangSan (3 capsules/time, 3 times/day)+Chinese herbal soup (LiuWeiDiHuangWan+XiangShaLiuJunZiTang) to strengthen the spleen and tonify the kidneys+a small dose of androgen sorally, which was maintained for a period of hematological improvement.The disease progressed from early 2020 to August 2020 with out systematic medication treatment. Thesymptoms: weakness, dizziness and tinnitus, palpitations, poorappetite, frequent nocturnal urination, normal bowel movements, pale mouth, pale tongue, smooth and white coating, slightly yellowish greasy tongue root. The pulse is sunken and thin.,TCM diagnosis, marrow consumption ; spleen and kidney deficiency, toxicity and stasis blockage.,Western medicine diagnosis, Myelodysplastic syndrome with primo cytosis (MDS, EB-1),Therapeutic methods, Compound QingHuangSan (3 capsules/time, 3 times/day) + Chinese herbal soup for strengthening the spleen and tonifying the kidney (LiuWeiDiHuangWan + XiangShaLiuJunZiTang) + oral treatment with small doses of androgens.,Clinical outcomes, weakness, dizziness and tinnitus, palpitations and other discomforts subsided; hematological improvement at 6 months and complete remission at 12 months.
骨髓增生异常综合征髓毒劳复方青黄散健脾补肾小剂量雄激素【适合阅读专业】 血液病肿瘤
Myelodysplastic syndromeMarrow consumptionCompound QingHuangSanStrengthening the spleen and tonifying the kidneyLow-dose androgens【Suitable majors】 HematologyOncology
宋敏敏,王月,方苏,等.胡晓梅温阳化毒治疗骨髓增生异常综合征经验[J]. 中国中医药信息杂志,2014,21(8):109-111.
范腾,肖海燕,朱千赜,等.口服含砷中药复方青黄散治疗骨髓增生异常综合征患者生存期分析[J]. 中华临床医师杂志(电子版),2019,13(8):561-565.
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