Summary of case history,　Patient, female, 16 years old. The main clinical manifestation was menstrual cycle delayed by more than 2 years after the drug, and now amenorrhea for 8,+, months". The patient had menarche at the age of 13 and had regular menstruation in the past. After taking prednisone acetate for treatment of anaphylactoid purpura nephritis 2 years ago, she developed necrosis of the right femoral head, and her menstrual cycle was delayed. After stopping the medication, her menstrual cycle still did not return to normal. Abdominal color ultrasound showed polycystic changes in both ovaries. Sex hormone test: prolactin (PRL): 222 uIU/mL, follicle stimulating hormone (FSH): 4.68 mIU/mL, luteinizing hormone (LH): 12.9 mIU/mL, estradiol (E2): 54.2 pg/mL, progesterone (P): 0.14 ng/mL, testosterone (T): 83.6 ng/dL, free testosterone (FT): 4.71 pg/mL, dehydroepiandrosterone sulphate(DHEA-S): 74.36 nmol/L. Insulin release test indicates hyperinsulinemia. Now she come to Hospital of Chengdu University of TCM for treatment of restore the menstrual cycle with Traditional Chinese medicine.,Symptoms and signs,　Fat body, eat and sleep well, Normal urination and urination, dull-red tongue, white tongue fur, slippery and slightly rapid pulse.,TCM treatment,　Nourish kidney and blood-activating, reduce phlegm and dampness.,TCM diagnosis,　Amenorrhea, kidney-deficiency and blood-stasis with phlegm and dampness syndrome.,Western medicine diagnosis,　Secondary amenorrhea; Adolescent polycystic ovary syndrome; Hyperinsulinemia; Hyperandrogenemia.,Therapeutic methods,　Traditional Chinese comprehensive treatment (Chinese herbal decoction, Tongmai Dasheng tablet, TCM characteristic therapy),Clinical outcomes,　After more than 1 months of treatment with traditional Chinese medicine alone, has resume menstruation. And after treated for a total of 6 months, the menstrual cycle, period and menstrual volume was basically returned to normal.