Summary of case history　,LV,female, 56 years old. Her first diagnosis time: May 20, 2016.Main complaint: blood sugar increased for 5 years and irritability for 3 years. History of Present Illness:The patient was diagnosed as "type 2 diabetes" 5 years ago, and was treated with oral hypoglycemic drugs. Three years ago, she was diagnosed with "depression" because of emotional abnormalities,irritability and insomnia after life events. She was once treated with Zoloft. Recently she was stimulated by life events, poor blood sugar control, irritable and difficult to sleep. She wanted to seek Traditional Chinese Medicine treatment.Symptom Impatient and irritable, dry mouth and bitter mouth, constipation, poor sleep, dark red tongue, yellow and greasy fur, slightly fast pulse string.,TCM diagnosis,　Xiaoke (Pattern of depressed Liver Qi transforming into fire,dampness-heat and blood stasis), Yuzheng (Pattern of depressed Liver Qi transforming into fire, dampness-heat and blood stasis).,Western medicine diagnosis,　type 2 diabetes,depression.,Therapeutic methods,　1.Emotional counseling and lifestyle education Professor Fan encouraged the patient to participate in social activities to enhance treatment confidence. In addition,he suggested that food intake should be reduced appropriately, and she should walk for half an hour to one hour after dinner every day, and drink a small amount of 2 liters of Chinese herbal decoction frequently.The method of decoction of traditional Chinese medicine: take a 4L medicine pot, add 3L water,decoct it into 2L and drink it frequently. 2.Chinese Medicine Chinese Medicine internal therapy clearing liver and relieving depression,clearing away heat and dampness,cool and invigorate blood. Chinese Medicine Prescription: Chaihu (Radix Bupleuri) 5 g、Baishao (Radix Paeoniae Alba) 30 g、Bohe (Herba Menthae) 5 g(later)、Mudanpi (Cortex Moutan) 15 g、Baizhu (Atractylodes macrocephala Koidz.) 30 g、Shengdihuang (Rehmanniae Radix) 30 g、Lianqiao (Forsythia suspensa) 10 g、Danzhuye (lophatherum herb) 10 g、,Jiuchuanniuxi (Wine Cyathulae Radix silce) 15 g、Yimucao (Herba Leonuri) 15 g、Ezhu (Curcumae Rhizoma) 10 g、Danshen (Salvia miltiorrhiza Bge.) 30 g、Shouwuteng (Caulis Polygoni Multiflori) 15 g、Gancao (Glycyrrhiza uralensis Fisch.) 5 g.One medicaments a day,decocted with water. She visited the outpatient clinic regularly, and Professor Fan adjusted her Chinese medicine plan.She totally took more than 120 doses of traditional Chinese medicine.,Clinical outcomes,　On October 16, 2016, the patient tended to be calm, sleep improved, and her stool was normal. The fasting blood glucose was 6.4mmol/l and the glycated hemoglobin was 6.8%.