Summary of case history,　Ms. Lv, 49 years old, female cadre, married, Han nationality, came to see a doctor because of the symptoms of hot sweat and other symptoms for more than 2 months and aggravation for 1 week, half a year after oophorectomy. The patient had regular menstruation in the past, cycle of 26-28 days, period of 5-7 days, moderate amount of menstruation, dark red color, occasional blood clots, mild abdominal pendant pain and discomfort during menstruation, which could be tolerated. LMP: August 5, 2021. Half a year ago, she underwent laparoscopic total hysterectomy plus bilateral adnexectomy due to uterine fibroids, and recovered well after operation without obvious discomfort. Patients with paroxysmal baking hot 2 month ago, clouds, sweat out, at the same time with insomnia, much dream, upset, irritability, anxiety, can whole body fatigue, lumbar acid trapped with occasional discomfort, pharynx GanYan itch, chest have a fever, feed commonly, occasional hiccups, abdominal distension, dry stool, line 1, 2-3, urine normal, tongue is red, moss thin, slightly string pulse count.,TCM diagnosis,　Menopausal syndrome(Fire excess from yin deficiency and heart-kidney disharmon syndrome),Western medicine diagnosis,　Menopausal syndrome;After hysterectomy,Therapeutic methods,　Professor He Fengjie was given modified Nian Zhishen decoction designed by himself,Clinical outcomes,　In patients with the first option, and enter the menopausal transition, appeared in paroxysmal hot flashes, as the, sweat out, at the same time with insomnia, much dream, upset, irritability, anxiety, can whole body fatigue, lumbar acid trapped with occasional discomfort, pharynx GanYan itch, chest have a fever, feed commonly, occasional hiccups, abdominal distension, dry stool, and a series of symptoms of the menopausal transition, After the adjustment by Professor He Fengjie using the self-designed Gengnian Jizhen Decoction, the symptoms of hot and irritable were significantly improved, the sweat was relieved, the stool was unobtrated, which could be maintained once a day, the stomach was vibrating, and the sleep and fatigue were slightly improved. The correctness and effectiveness of syndrome differentiation and drug use were proved. On the basis of the original prescription, we continued to adjust the three diagnosis combined with the patient's clinical symptoms. The patient's symptoms of baking enthusiasm and annoyance disappeared, the night sleep gradually calmed down, the mood was stable as before, the life was free, and the self-confidence gradually returned to normal.