张宁治疗痛风经验采撷
增强出版ZHANG Ning's Experience in Treating Gout
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1.北京中医药大学,北京 100029
2.中国中医科学院望京医院肾病内分泌科,北京 100102
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于芳宁, 张宁. 张宁治疗痛风经验采撷[DB/OL].(2023-03-18)[2023-11-05].http://cccl-tcm.cacm.org.cn/thesisDetails?columnId=35601615&Fpath=home&index=0
YU Fangning, ZHANG Ning. ZHANG Ning's Experience in Treating Gout[DB/OL].(2023-03-18)[2023-11-05].http://cccl-tcm.cacm.org.cn/thesisDetails?columnId=35601615&Fpath=home&index=0
于芳宁, 张宁. 张宁治疗痛风经验采撷[DB/OL].(2023-03-18)[2023-11-05].http://cccl-tcm.cacm.org.cn/thesisDetails?columnId=35601615&Fpath=home&index=0 DOI:
YU Fangning, ZHANG Ning. ZHANG Ning's Experience in Treating Gout[DB/OL].(2023-03-18)[2023-11-05].http://cccl-tcm.cacm.org.cn/thesisDetails?columnId=35601615&Fpath=home&index=0 DOI:
病史摘要,2,孙某,男,26岁,2020年10月27日初诊,以“左手肿胀疼痛2月”就诊。2年前体检发现血尿酸升高,未服药,2020年3月出现痛风,口服秋水仙碱后好转。近2个月左手发胀,左中指近端指间关节压痛。刻下:左手发胀,左中指近端指间关节压痛,时有头晕,食后腹胀,口干口苦,双目干涩,自觉四肢酸懒沉重,疲倦。纳可,眠差,大便溏,日1次,小便黄,有异味。舌红苔黄腻,脉滑。辅助检查:2020年10月27日,生化:尿酸592 μmol/L,甘油三酯6.36 mmol/L,低密度脂蛋白胆固醇3.98 mmol/L,余未见异常。诊间测血压145/90 mmHg。中医诊断 痹症,肝胆湿热证西医诊断 1.痛风;2.高尿酸血症;3.高脂血症;4.高血压1级(中危组);5.脂肪肝。干预措施 中药予小柴胡汤合四妙散加减,原方如下:柴胡10 g、黄芩10 g、车前草15 g、薏苡仁30 g、苍术10 g、黄柏10 g、川牛膝15 g、萆薢15 g、五味子10 g、白芍10 g、佛手10 g、菊花15 g、炒枣仁30 g、竹叶10 g、生甘草3 g。颗粒剂7付,水冲200 mL,分早晚2次口服。西医治疗以减少尿酸生成为主,予别嘌醇2.5 mg,口服,每天1次。疗效转归 11月5日复诊:手胀痛好转,未发作头晕,夜眠较前改善,精神好转。便溏。舌红,脉滑。原方加土茯苓10 g、威灵仙10 g,7付,服法同前。11月19日复诊:手胀痛完全缓解,未发作头晕,夜眠可,体力精神基本恢复正常,偶有腰酸,大便不成形。复查生化:尿酸403 μmol/L,甘油三酯5.7 mmol/L,低密度脂蛋白胆固醇2.03 mmol/L,上方加续断15 g、金钱草15 g、车前草增至30 g,14付,服法同前。服药后诸症悉除。
Summary of case history, Patient Sun , male, 26 years old, was diagnosed for the first time on October 27, 2020, with "swelling and pain in his left hand for 2 months". Two years ago, the physical examination found that serum uric acid was elevated, but without taking medicine. Gout developed in March 2020, and it was improved after oral administration of colchicine. In the past 2 months, the left hand was swollen, and the proximal interphalangeal joint of the left middle finger was tender.. Symptoms: left hand swollen, tenderness in the proximal interphalangeal joint of the left middle finger, dizziness, abdominal distention after eating, dry mouth, dry eyes, feeling that the limbs are sore and heavy, and tired. Naco, poor sleep, loose stools, once a day, yellow urine with a peculiar smell. Red tongue, yellow greasy coating, slippery pulse. Auxiliary examination: 2020-10-27 Biochemical: uric acid 592 umol/L, triglyceride 6.36 mmol/L, low-density lipoprotein cholesterol 3.98 mmol/L, no abnormality was found. Immediately measure blood pressure 145/90 mmHg.,TCM diagnosis ,Bizheng Gandanshirezheng,Western medicine diagnosis, 1. Gout;2. Hyperuricemia;3. Hyperlipidemia;4. Hypertension grade 1 (intermediate risk group);5. Fatty liver.,Therapeutic methods ,We gave him xiao chai hu tang and si miao san, the specific drugs were as follows: Bupleuri Radix 10 g,Scutellariae radix 10 g,Plantaginis herba 15 g,Coicis semen 30 g,Atractylodis rhizoma 10 g,Phellodendri Chinese cortex 10 g,Cyatjulae radix 15 g,Dioscoreae spongiosae rhizoma 15 g,Schisandrae Chinese fructus 10 g,Paeoniae radix alba 10 g,Citri sarcodactylis fructus 10 g,Chrysanthemi flos 15 g,Ziziphi spinosae semen 30 g,Lophatheri herba 10 g,Glycyrrhizae radix rhizoma 3 g. Western medicine treatment wasmainly to reduce the production of uric acid, and allopurinol was given orally at 2.5 mg Qd.,Clinical outcomes, Follow-up on November 5: Hand pain improved, no dizziness occurred, night sleep improved than before, and spirit improved. loose stools. Red tongue, slippery pulse. The original recipe added Smilacis glabrae rhizoma 10 g and Clematidis radix et rhizoma 10 g, 7 pieces, the dosage was the same as before. Follow-up consultation on November 19: The pain in the hand was completely relieved, dizziness did not occur, and the night sleep was fine. Recheck biochemistry: uric acid 403 umol/L, triglyceride 5.7 mmol/L, low-density lipoprotein cholesterol 2.03 mmol/L, add Dipsaci radix 15 g,Lysimachiae herba 15 g and Plantaginis herba 30 g, 14 doses, the dosage was the same as before. After taking the medicine, all the symptoms has been removed.
高尿酸血症痛风经验总结
HyperuricemiaGoutExperience summary
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