This paper summarized WANG Shuchen's clinical experience in treating pulmonary nodules from the latent pathogen theory. It is believed that healthy,qi,depletion and latent pathogen into collaterals are the key pathogenesis of pulmonary nodules， for which clearing latent pathogen and reinforcing healthy,qi,is the main target. The methods of dissipating masses and searching and eliminating pathogens should be combined； usually it is recommended to clear latent pathogen and dissipate masses by soothing the liver and moving,qi,， breaking up blood and dissolving stasis， clearing the lung and dispelling phlegm， softening hardness and dissipating masses， or clearing heat and resolving toxins， and to search and eliminate pathogens with rattan medicinals or insects entering the colla-terals. Simultaneously， the methods of fortifying the spleen and supplementing the lung， and nourishing the heart and opening the orifices can be used to dispel pathogen and reinforce healthy,qi,， disperse and dissipate nodules.