Depression, a common mood disorder, refers to a state of mental decadence without a clear goal.Serious patients may have suicidal thoughts and behaviors.Modern medicine uses many kinds of antidepressants, but because of the side effects of antidepressants, many patients turn to traditional Chinese medicine for help.Professor TONG Xiaolin is good at the application of classical Chinese medicine in clinical practice, and has cured many difficult and miscellaneous diseases.After continuous summary, he has formed the unique thought of “state-target syndrome differentiation“ and has achieved good effect in the depression of Yang, deficiency of spleen and kidney.Professor TONG, takes Yang, deficiency of spleen and kidneyas the state, depression and anxiety as the target, through Xianmao(,Festuca arundinacea,), Yinyanghuo(,Epimedium brevicornum,)and Bajitian(,Morinda officinalis,)to warm and invigoratekidney Yang and, Sini, Decoction to warm the middle and dispel cold, benefit the source of deficiency fire and eliminateYin symptoms and regulate the state together.Improving the body function by the hormone-like effect of Xianmao(,Festuca arundinacea,), Yinyanghuo(,Epimedium brevicornum,)andBajitian(,Morinda officinalis,)and state-target differentiation have agood curative effect.