Professor WANG Qing-guo excels in using classical prescriptions, while not limited to them. Therefore, when dealing with complex conditions, he can always solve effectively. Through the targeted analysis of 4 typical medical records, it is concluded that professor WANG’s treatment of coronary heart disease is mainly based on deficiency and excessiveness, and syndrome differentiation based on viscera status is the core. At the same time, it points out that the incidence of coronary heart disease is mostly due to excessiveness resulting from deficiency, and intermingled deficiency and excessiveness. Specifically, it mainly includes heart and spleen deficiency, sputum and fluid retention, stagnation of liver qi and spleen deficiency, qi deficiency and blood stasis, devitalized heart yang, turbid phlegm blockage, qi and yin deficiency, and stasis obstructing heart vessels.In addition to that, this article also summarizes professor WANG’s experience in using pair medicines, triplet medicines and emphasis on pharmacology. Through the summary of professor WANG’s experience in the diagnosis and treatment of coronary heart disease, it is expected to be helpful to later scholars.