Endometriosis is a common and difficult gynecological disease.The incidence of endometriosis has been increasing year by year.Because endometriosis mostly occurs in childbearing age, it can cause persistent damage to the fertility of patients, and is an important cause of infertility.Although endometriosis is a benign disease, it has malignant behavior, and is easy for relapse and metastasis and difficult to treat in clinic.Early diagnosis, comprehensive evaluation, formulation of programs and timely treatment play an important role in protecting patients'fertility.The pathogenesis of endometriosis is still unclear in modern medicine.Drugs, surgery and assisted reproductive technology are the main therapies.The author has achieved a good efficacy in the long-term treatment of infertility due to endometriosis.She believes that the disease is caused by kidney deficiency and blood stasis.They are cause and effect to each other, which form a vicious circle.In view of the basic pathogenesis of kidney deficiency and blood stasis, we should make good use of the method of Bushen Huoxue, and emphasize the treatment by stages:promoting blood circulation and removing blood stasis, and treating diarrhea with purgative in the menstrual stage;nourishing kidney and blood, and regulating thoroughfare and conception vessels in the postmenstrual stage;warming kidney and supporting Yang, and dredging collaterals and hastening excretion in the interval stage;and tonifying kidney and spleen, and managing Qi and activating blood in the premenstruum stage.Leech is commonly adopted in clinic prescriptions to remove accumulation of persistent blood stasis and regulate mood, and combined with enema of traditional Chinese medicine, hot compress and other external therapies to enhance the curative effect.