活用晁恩祥“精参五味方”治疗重症新冠肺炎后胸闷、气促医案1则
A Case of Using CHAO Enxiang's "Jing Shen Wu Wei Formula" In Treatment of Chest tightness and Shortness of Breath After Severe COVID-19 Pneumonia
收稿日期:2024-08-22,
录用日期:2024-12-13,
网络出版日期:2025-08-09
移动端阅览
1.福建中医药大学,福州 350122
2.福建中医药大学附属第二人民医院肺病科,福州 350003
收稿日期:2024-08-22,
录用日期:2024-12-13,
网络出版日期:2025-08-09,
移动端阅览
李文明,王春娥.活用晁恩祥“精参五味方”治疗重症新冠肺炎后胸闷、气促医案1则[DB/OL].(2022-01-01)[2022-03-10].http://cccl-tcm.cacm.org.cn/thesisDetails#10.19879/j.cnki.1005-5304.202002478&lang=zh
LI Mingwen,WANG Chune.A Case of Using CHAO Enxiang's "Jing Shen Wu Wei Formula" In Treatment of Chest tightness and Shortness of Breath After Severe COVID-19 Pneumonia[J].,
李文明,王春娥.活用晁恩祥“精参五味方”治疗重症新冠肺炎后胸闷、气促医案1则[DB/OL].(2022-01-01)[2022-03-10].http://cccl-tcm.cacm.org.cn/thesisDetails#10.19879/j.cnki.1005-5304.202002478&lang=zh DOI:
LI Mingwen,WANG Chune.A Case of Using CHAO Enxiang's "Jing Shen Wu Wei Formula" In Treatment of Chest tightness and Shortness of Breath After Severe COVID-19 Pneumonia[J]., DOI:.
病史摘要
2
蒲某,女,59岁,因“咳嗽伴活动后气促1月余,加重1天”就诊.患者缘于1月余前,受凉后出现干咳,自行服用口服药物(具体不详)后自觉稍好转。但2天后无明显诱因出现腹泻,7~8次/天,伴咳嗽、气喘,自测新冠病毒抗原阳性,急诊福州市某三甲医院,予胸部CT平扫示:双肺病毒性肺炎。拟“肺炎、新型冠状病毒感染”,予“舒普深抗感染、甲泼尼龙抗炎”等治疗,病情恶化,出现呼吸衰竭,诊为“重症肺炎”转入ICU,先后予无创呼吸机辅助呼吸(2023年1月7日~2023年1月25日)、高流量给氧(2023年1月25日~2023年1月31日),奈玛特韦/利托那韦抗病毒、甲泼尼龙抗炎(2023年1月5日~2023年1月16日),舒普深(2023年1月5日~2023年1月13日)、美罗培南(2023年1.13日~2023年2月1日)、卡泊芬净(2023年1月16日~2023年2月1日)抗感染,氨溴索化痰、低分子肝素抗凝治疗30天后,病情好转,复查血气示氧分压84.1 mmHg,于2月4日出院。1天前气促症状加重,家用脉氧仪自测血氧饱和度92%,遂就诊福建中医药大学附属第二人民医院门诊。刻下症:咳嗽,痰黄量多,胸闷,伴气促,周身乏力,口干,纳呆,寐可,二便调。舌质红,苔黄腻,脉细。中医诊断 喘证(气阴两虚、痰热郁肺兼血瘀证)。西医诊断 重症肺炎(新型冠状病毒感染)恢复期。干预措施 中药治疗,选用晁恩祥教授创立的“精参五味方”为基础方,以益气养阴、清热化痰、兼以活血化瘀为基本治法,同时结合患者症状,辨证论治,适时更方。疗效转归 中药治疗1个月后,患者胸闷、气促症状明显改善,血氧饱和度恢复到95%以上,因肺部间质性病变弥漫,为避免遗留纤维化,继续中药调理2个月,后于2023年5月3号在福建中医药大学附属第二人民医院复查胸部CT,病灶基本吸收。
Summary of case history
PU
female
59 years old
consulted for "cough with shortness of breath after activity for more than 1 month
aggravated for 1 day". The patient had a dry cough after a cold spell more than a month ago
and felt slightly better after taking oral medications (details unknown). But 2 days later
no obvious cause of diarrhea
7~8 times / day
with cough
shortness of breath
self-assessment of the new coronavirus antigen-positive
no fever
chills
no hemoptysis
chest pain
no nausea
vomiting and other discomforts
emergency treatment of Fuzhou City
a tertiary hospital
to the CT scanning of the chest showed that: bilateral viral pneumonia
a small amount of bilateral pleural effusion. The patient was diagnosed with "pneumonia and COVID-19 infection"
and was given Shupu Shen anti-infection and Methylprednisolone anti-inflammatory treatments. His condition deteriorated and he developed respiratory failure
and was transferred to ICU with "severe pneumonia". He was transferred to ICU
and was successively given non-invasive ventilator-assisted respiration (January 7
2023 to January 25
2023)
high-flow oxygen (January 25
2023 to January 31
2023)
nirmatrelvir/ritonavir antiviral treatment
methylprednisolone (January 5
2023 to January 16
2023) anti-inflammatory treatment
sulphenesin (January 5
2023 to January 13
2023)
meropenem (January 13
2023 to February 1
2023)
caspofungin (January 16
2023 to February 1
2023) anti-infective treatment
ambroxol to reduce phlegm
and anticoagulation with low molecular heparin.After 30 days of treatment
the condition improved
and the partial pressure of oxygen in the rechecked blood gases was 84.1 mmHg
and she was discharged from the hospital on February 4
2023. 1 day ago
the symptoms of shortness of breath were aggravated
and the oxygen saturation level was 92% measured by pulse
oximeter at home
so she visited the outpatient clinic of our hospital. Current symptoms: cough
yellow sputum
chest tightness
accompanied by shortness of breath
fatigue
dry mouth
nausea
sleep
bowel movement. The tongue was red
the moss was yellow and greasy
and the pulse was fine.
TCM diagnosis
Dyspnea disease(deficiency of Qi and Yin
phlegm and heat around the lungs and evidence of blood stasis).
Western medicine diagnosis
Convalescence period of severe pneumonia (COVID-19).
Therapeutic methods
For traditional Chinese medicine (TCM) treatment
the " Jing Shen Wu Wei Formula" created by Professor CHAO Enxiang is selected as the basic formula
with the basic treatment method of invigorating Qi and nourishing Yin
dispel heat and transform phlegm
invigorate blood circulation and eliminate blood stasis combined with the symptoms of patients
dialectical treatment.
Clinical outcomes
After 1 month of TCM treatment
the patient's symptoms of chest tightness and shortness of breath improved significantly
and the oxygen saturation level recovered to more than 95%. Chest CT shows the diffuse interstitial lesions in the lungs
in order to avoid the residual fibrosis
the patient continued to be treated by TCM for 2 months
and then he was rechecked by chest CT in
Second Affiliated Hospital of Fujian University of Traditional Chinese Medicine
on May 3
2023
and the lesions were basically absorbed.
新型冠状病毒感染诊疗方案(试行第十版) [J ] . 中国医药 , 2023 , 18 ( 2 ): 161 - 166 .
靳鑫 , 李晨浩 , 张洪春 . 晁恩祥教授治疗新型冠状病毒肺炎经验 [J ] . 中日友好医院学报 , 2022 , 36 ( 5 ): 307 - 308 .
王琦 , 谷晓红 , 刘清泉 . 新型冠状病毒肺炎中医诊疗手册 [M ] . 北京 : 中国中医药出版社 . 2020 .
强晓钰 , 陈哲 , 季昭臣 , 等 . 中医药对新型冠状病毒肺炎(COVID-19)恢复期患者肺功能影响的Meta分析 [J ] . 环球中医药 , 2023 , 16 ( 2 ): 226 - 233 .
闫志鹏 , 吴杰 , 闫曙光 , 等 . 基于数据挖掘与网络药理学探讨新型冠状病毒肺炎恢复期中医药用药规律及机制 [J ] . 陕西中医药大学学报 , 2023 , 46 ( 5 ): 29 - 38 .
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