Effect of acupuncture in treating postprandial distress syndrome with spleen-stomach qi deficiency

Zou Xuan; Li Jinling; Yang Jingwen; Lin Lulu; Tu Jianfeng; Wang Yu; Liu Cunzhi

doi:10.3969/j.issn.1006-2157.2021.05.012

Suggestions

您当前的位置：

首页 >

文章列表页 >

Effect of acupuncture in treating postprandial distress syndrome with spleen-stomach qi deficiency

Previous: Professor ZHANG Zhiyuan's Experience in Using Chaihu (Radix Bupleuri)

Next: SONG Yeqiang’s Medication Experience in Treating Chronic Urticaria

Effect of acupuncture in treating postprandial distress syndrome with spleen-stomach qi deficiency
1.International Acupuncture and Moxibustion Innovation Institute, School of Acupuncture-Moxibustion and Tuina, Beijing University of Chinese Medicine, Beijing 100029, China
2.School of Acupuncture-Moxibustion and Tuina, Beijing University of Chinese Medicine, Beijing 100029, China
3.Beijing Hospital of Traditional Chinese Medicine Affiliated to Capital Medical University, Beijing 100010, China
DOI：10.3969/j.issn.1006-2157.2021.05.012

扫描看全文

Zou Xuan, Li Jinling, Yang Jingwen, et al. Effect of acupuncture in treating postprandial distress syndrome with spleen-stomach qi deficiency[DB/OL].（2023-09-15）[2023-11-05].http://cccl-tcm.cacm.org.cn/thesisDetails#10.3969/j.issn.1006-2157.2021.05.012
DOI：

Zou Xuan, Li Jinling, Yang Jingwen, et al. Effect of acupuncture in treating postprandial distress syndrome with spleen-stomach qi deficiency[DB/OL].（2023-09-15）[2023-11-05].http://cccl-tcm.cacm.org.cn/thesisDetails#10.3969/j.issn.1006-2157.2021.05.012 DOI：

摘要

目的,2,观察针刺治疗餐后不适综合征（PDS）脾胃气虚证的临床疗效。,方法,2,对108例PDS脾胃气虚证患者进行回顾性分析，针刺组55例，假针组53例。针刺组采用传统针刺干预，穴取百会、膻中、中脘、气海、天枢、内关、足三里、公孙和太白穴；假针组采用非穴浅刺干预。2组均留针20 min，每周针刺3次，连续治疗4周，治疗结束后随访12周。比较2组在治疗结束和随访结束后消化不良症状指数（SID）、尼平消化不良指数（NDI）、医院焦虑抑郁量表（HADS）评分较治疗前的变化，进行疗效评价和安全性评价。,结果,2,4周治疗结束后，针刺组有效率为72.7%，高于假针组45.3%（,P,<,0.05）。治疗4周后，针刺组的SID总分、NDI评分的下降幅度均高于假针组（,P,<,0.05），且在治疗结束后持续12周（,P,<,0.05）。治疗4周后，针刺组HADS评分的下降幅度高于假针组（,P,<,0.05），但随访期间组间比较无差异。研究期间未报告严重不良事件。,结论,2,针刺能够改善PDS脾胃气虚证患者的消化不良症状、生活质量，并能持续到治疗结束后12周；针刺能改善患者焦虑抑郁情绪，但这一效应在针刺结束后并不能持续存在。

Abstract

Objective,2,To observe the clinical effect of acupuncture on postprandial distress syndrome(PDS)with spleen-stomach qi deficiency.,Methods,2,A retrospective analysis was conducted in 108 eligible PDS patients, with 55 cases in the acupuncture group and 53 cases in the sham acupuncture group. The patients in the acupuncture group were treated by acupuncture at Baihui(DU20), Danzhong(RN17), Zhongwan(RN12), Qihai(RN6), Tianshu(ST25), Neiguan(PC6), Zusanli(ST36), Gongsun(SP4)and Taibai(SP3). A superficial skin penetration at non-acupoints was performed in the sham acupuncture group. The patients in both groups were treated for 3 sessions(20 minutes per ses-sion)per week for 4 weeks, and were followed up 12 weeks after the last session. The changes of Symptom Index of Dyspepsia(SID), Nepean dyspepsia index(NDI)and Hospital Anxiety and Depression Scale(HADS)scores were compared between the two groups after the last session and 12 weeks after the treatment, so as to evaluate the efficacy and safety.,Results,2,After 4 weeks of treatment, the effective rate of the acupuncture group was 72.7%, higher than 45.3% of the sham acupuncture group(,P,<,0.05), and the descender of SID and NDI scores of the acupuncture group were greater than those of the sham acupuncture group(,P,<,0.05)and lasted for 12 weeks after treatment(,P,<,0.05). After 4 weeks of treatment, the descender of HADS score in the acupuncture group was greater than that of the sham group(,P,<,0.05), but there was no significant difference between the two groups during follow-up period. No serious adverse events were reported during the study period.,Conclusion,2,Among PDS patients with spleen-stomach qi deficiency, acupuncture could reduce the symptoms of indigestion, improve the quality of life, with sustained efficacy over 12 weeks in patients who have received acupuncture treatment for 4 weeks, three times each week. Acupuncture seems to alleviate the patient's anxious and depressive emotions, but this effect does persist when the treatmentends.

关键词

餐后不适综合征脾胃气虚证针刺消化不良症状生活质量焦虑抑郁情绪

Keywords

postprandial distress syndrome(PDS)spleen-stomach qi deficiencyacupunctureindigestionquality of lifeanxious and depressive emotions

references

Van Den Houte K, Carbone F, Tack J. Postprandial dis-tress syndrome: stratification and management[J]. Expert Rev Gastroenterol Hepatol, 2019, 13(1):37-46.

Stanghellini V, Chan FKL, Hasler WL, et al. Gastroduo-denal disorders[J]. Gastroenterology, 2016, 150(6):1380-1392.

Tack J, Van den Houte K, Carbone F. The unfulfilled promise of prokinetics for functional dyspepsia/postprandial distress syndrome[J]. Am. J. Gastroenterol, 2019, 114(2):204-206.

Aziz I, Palsson OS, Törnblom H, et al. Epidemiology, clinical characteristics, and associations for symptom-based RomeⅣfunctional dyspepsia in adults in the USA, Cana-da, and the UK: across-sectional population-based study[J]. Lancet Gastroenterol Hepatol, 2018, 3(4):252-262.

Potter M, Talley NJ. New insights into functional dyspepsia: further evidence for postprandial distress syndrome as a distinct disease[J]. Lancet Gastroenterol Hepatol, 2018, 3(4):217-218.

Aziz I, Palsson OS, Törnblom H, et al. The prevalence and impact ofoverlapping RomeⅣ-diagnosed functional gastrointestinal disorders on somatization, quality of life, and healthcare utilization: across-sectional general population study in three countries[J]. Am J Gastroenterol, 2018, 113(1):86-96.

Sperber AD, Bangdiwala SI, Drossman DA, et al. World-wide prevalence and burden of functional gastrointestinal disorders, results of Rome Foundation global study[J]. Gastroenterology, 2021, 160(1):99-114.e3.

杜庆红.心理护理对功能性消化不良患者负性情绪的影响及效果分析[J]. 心理月刊, 2020, 15(13):81.

Du QH. Effect of psychological nursing on negative emotion of patients with functional dyspepsia[J]. PSY, 2020, 15(13):81.

吕林, 王凤云, 唐旭东, 等.脾虚1号方对功能性消化不良脾虚证大鼠胃体组织MLC蛋白与基因表达的影响[J]. 北京中医药大学学报, 2017, 40(9):729-735.

Lyu L, Wang FY, Tang XD, et al. Influence of Pixu Fang 1(Spleen-deficiency Formula 1)on protein and gene ex-pressions of myosin light chain in rats with functional dyspepsia-spleen deficiency pattern[J]. Journal of Beijing U-niversity of Traditional Chinese Medicine, 2017, 40(9):729-735.

Hou YQ, Zhang X, Tu JF, et al. Efficacy of acupuncture versus sham acupuncture for postprandial distress syndrome: study protocol for a randomized controlled trial[J/OL]. Trials, 2019, 20(1):65[2020-10-23]. https://trialsjournal.biomedcentral.com/articles/10.1186/s13063-018-3051-3https://trialsjournal.biomedcentral.com/articles/10.1186/s13063-018-3051-3.

Yang JW, Wang LQ, Zou X, et al. Effect of acupuncture for postprandial distress syndrome: a randomized clinical trial[J]. Ann Intern Med, 2020, 172(12):777-785.

中国中西医结合学会消化系统疾病专业委员会.功能性消化不良的中西医结合诊疗共识意见(2010)[J]. 中国中西医结合杂志, 2011, 31(11):1545-1549.

Digestive Diseases Committee of Chinese Association of Integrated Traditional and Western Medicine. Consensus on diagnosis and treatment of functional dyspepsia with integrated Chinese and western medicine(2010)[J]. Chinese Journal of Integrated Traditional and Western Medicine, 2011, 31(11):1545-1549.

石学敏, 张存生, 刘白雪, 等.捻转补泻手法的应用及其量学概念[J]. 中国医药学报, 1987, 2(5):16-17.

Shi XM, Zhang CS, Liu BX, et al. Application of twirling reinforcing and reducing manipulation and its quantitative concept[J]. China Journal of Traditional Chinese Medicine and Pharmacy, 1987, 2(5):16-17.

Yang JW, Zhang LW, Shi GX, et al. Acupuncture for postprandial distress syndrome(APDS): study protocol for a randomized controlled trial[J/OL]. Trials, 2017, 18(1):537[2020-10-27]. https://trialsjournal.biomedcen-tral.com/articles/10.1186/s13063-017-2285-9https://trialsjournal.biomedcen-tral.com/articles/10.1186/s13063-017-2285-9.

Jones MP, Sato YA, Talley NJ. The Nepean Dyspepsia Index is a valid instrument for measuring quality-of-life in functional dyspepsia[J]. Eur J Gastroenterol Hepatol, 2019, 31(3):329-333.

Miljanovic M, Sindik J, Milunovi? V, et al. Factor structure and cut-off scores of the Hospital Anxiety and Depression scale(HADS)in a Croatian sample of adult patients suffering from advanced cancer[J]. Psychiatr Danub, 2017, 29(4):451-458.

王德凤, 蔡琳.热性针灸治疗冈上肌钙化性肌腱炎的临床研究[J]. 北京中医药大学学报, 2019, 42(7):611-616.

Wang DF, Cai L. Calcifying tendinitis of the supraspinatus treated with thermo-acupuncture: a randomized controlled trial[J]. Journal of Beijing University of Traditional Chinese Medicine, 2019, 42(7):611-616.

Matsueda K, Hongo M, Tack J, et al. A placebo-controlled trial of acotiamide for meal-related symptoms of functional dyspepsia[J]. Gut, 2012, 61(6):821-828.

Vandenberghe A, Schol J, Van den Houte K, et al. Current and emerging therapeutic options for the management of functional dyspepsia[J]. Expert OpinPharmacother, 2020, 21(3):365-376.

Enck P, Azpiroz F, Boeckxstaens G, et al. Functional dyspepsia[J/OL]. Nat Rev Dis Primers, 2017, 3(3):17081[2020-10-27]. https://www.nature.com/articles/nrdp201781https://www.nature.com/articles/nrdp201781.

Tack J, Camilleri M. New developments in the treatment of gastroparesis and functional dyspepsia[J]. Curr Opin Pharmacol, 2018, 43:111-117.

Pittayanon R, Yuan YH, Bollegala NP, et al. Prokinetics for functional dyspepsia: a systematic review and meta-a-nalysis of randomized controltrials[J]. Am J Gastroenterol, 2019, 114(2):233-243.

Tack J, Pokrotnieks J, Urbonas G, et al. Long-term safety and efficacy of acotiamide in functional dyspepsia(postprandial distress syndrome)‐results from the European phase 3 open‐label safety trial[J]. Neurogastroenterol Motil, 2018, 30(6): e13284[2020-10-27]. doi: 10.1111/nmo.13284http://doi.org/10.1111/nmo.13284.

Lahner E, Bellentani S, Bastiani RD, et al. A survey of pharmacological and nonpharmacological treatment of functional gastrointestinal disorders[J]. United European Gastroenterol J, 2013, 1(5):385-393.

中国中西医结合学会消化系统疾病专业委员会.功能性消化不良中西医结合诊疗共识意见(2017年)[J]. 中国中西医结合消化杂志, 2017, 25(12):889-894.

Digestive Diseases Committee of Chinese Association of Integrated Chinese and Western Medicine. Consensus on diagnosis and treatment of functional dyspepsia by Integrated Chinese and Western Medicine(2017)[J]. Chinese Journal of Integrated Traditional and Western Medicine, 2017, 25(12):889-894.

唐燕, 唐梅文, 楼茜欣, 等.功能性消化不良的中医治疗进展[J]. 中医学报, 2020, 35(2):299-303.

Tang Y, Tang MW, Lou QX, et al. Advances in TCM treatment of functional dyspepsia[J]. Journal of Chinese Medicine, 2020, 35(2):299-303.

胡学军, 何桂花, 钟子劭.广州地区功能性消化不良的中医证型分布特点及相关性研究[J]. 广州中医药大学学报, 2017, 34(4):475-478.

Hu XJ, He GH, Zhong ZS. Distribution of Traditional Chinese Medicine syndrome types of functional dyspepsia in Guangzhou and their correlation with some factors[J]. Journal of Guangzhou University of Traditional Chinese Medicine, 2017, 34(4):475-478.

蓝莹, 高誉珊, 朱文莲, 等.比较电针“合谷”“足三里”穴对IBS模型大鼠结肠动力及结肠M3受体表达的影响[J]. 北京中医药大学学报, 2017, 40(12):1044-1049.

Lan Y, Gao YS, Zhu WL, et al. Comparing the colonic motility and expression of M3 muscarinic receptor in IBS rats by stimulating LI 4 and ST 36 with electroacupuncture[J]. Journal of Beijing University of Traditional Chinese Medicine, 2017, 40(12):1044-1049.

Koloski NA, Jones M, Kalantar J, et al. The brain-gut pathway in functional gastrointestinal disorders is bidirectional: a 12-year prospective population-based study[J]. Gut, 2012, 61(9):1284-1290.

李岩.功能性消化不良的心理评估及治疗策略[J]. 中国实用内科杂志, 2020, 40(2):96-99.

Li Y. Psychological assessment and treatment strategies for functional dyspepsia[J]. Chinese Journal of Practical Internal Medicine, 2020, 40(2):96-99.

Views

下载量

CSCD

Alert me when the article has been cited

提交

Tools

Publicity Resources

Seven Proved Cases of Mania

Experience of Professor WANG Zhaohui on Treating Peripheral Facial Paralysis

"Zhatiao" acupuncture technique for the treatment of cervical spondylosis

Experience of Prof. GUO Yi Treating Depression with Four-dredging Therapy

Effects of spleen-fortifying and kidney-replenishing therapy on manifestation and quality of life in patients with systemic lupus erythematosus disease

Related Author

No data

Related Institution

Sheqi Institute of Mental Illness of Traditional Chinese Medicine

Changchun University of Traditional Chinese Medicine

Baoan Essential Traditional Chinese Medicine Hospital

Beijing University of Chinese Medicine

Dongzhimen Hospital, Beijing University of Chinese Medicine

⁰