Sweat syndrome is a general term for diseases with abnormal sweat color, texture, amount of sweat, and smell, mainly including spontaneous sweating and night sweats. Professor Chen Xinyu has been engaged in traditional Chinese medicine education and clinical work for decades, and has unique insights into the treatment of sweat syndrome. This article attempts to summarize Professor Chen Xinyu’s experience in treating sweat syndrome through a summary of Professor Chen Xinyu’s three cases of sweat syndrome.