Experience of Chief Physician Zhang Linjun in Treating Liver Injury Induced by Anti-tumor Drugs

ZHANG Mengfan

doi:10.3969/j.issn.1003-8914.2020.15.013

Suggestions

您当前的位置：

首页 >

文章列表页 >

Experience of Chief Physician Zhang Linjun in Treating Liver Injury Induced by Anti-tumor Drugs

Experience of Chief Physician Zhang Linjun in Treating Liver Injury Induced by Anti-tumor Drugs
1.Beijing University of Chinese Medicine, Beijing 100029, China
DOI：10.3969/j.issn.1003-8914.2020.15.013

扫描看全文

ZHANG Mengfan. Experience of Chief Physician Zhang Linjun in Treating Liver Injury Induced by Anti-tumor Drugs[DB/OL].（2023-07-14）[2023-11-05].http://cccl-tcm.cacm.org.cn/thesisDetails#10.3969/j.issn.1003-8914.2020.15.013
DOI：

ZHANG Mengfan. Experience of Chief Physician Zhang Linjun in Treating Liver Injury Induced by Anti-tumor Drugs[DB/OL].（2023-07-14）[2023-11-05].http://cccl-tcm.cacm.org.cn/thesisDetails#10.3969/j.issn.1003-8914.2020.15.013 DOI：

摘要

抗肿瘤药物引起的肝损伤是药物性肝损伤的主要原因之一，张林军主任医师从事临床30余年，在恶性肿瘤及抗肿瘤药物引起肝损伤的中医治疗方面积累了丰富的临床经验。张林军主任认为抗肿瘤药物不良反应为外来之“药毒”，药毒戕伤正气，直中肝脏或脾胃，使肝主疏泄及脾司运化失常，湿浊内蕴，湿郁化热，湿热薰蒸肝胆引起肝损伤。治疗首重柔肝健脾、未病先防以提升肝脾对药毒之邪的抵御能力，临床上根据湿热轻重辨证施治，方证相对。

Abstract

Liver injury caused by anti-tumor drugs is one of the main causes of drug-induced liver injury. Chief Physician Zhang Linjun has been engaged in clinical practice for more than 30 years. He has accumulated rich clinical experience in the treatment of liver injury caused by malignant tumors and anti-tumor drugs in TCM. Director Zhang Linjun believes that the adverse reactions of anti-tumor drugs are foreign drug toxicity". The drug toxicity injures the vital energy, damages directly the liver or the spleen and stomach, and causes abnormal dispersion of the liver and transportation of the spleen, dampness and intrinsic contained, heat conversion of the dampness stagnancy, and umigating the liver and gallbladder with dampness and heat, Steaming liver and gall with damp heat makes the liver injury. The first priority f treatment is softening the liver and invigorating the spleen, preventing diseases before they occur, so as to enhance the resistance of the iver and spleen to the pathogens of drugs and poisons. Clinically, syndrome differentiation and treatment is basis of constitution of dampness nd heat, the prescriptions and syndromes are relative.

关键词

肿瘤肝损伤治未病中医药疗法张林军

Keywords

tumorliver injurypreventive treatment of diseasetherapy of TCMZhang Linjun

references

张惠娟, 史祖宣, 赵兰芳, 等.56例抗肿瘤药物致肝损伤临床特点分析[J]. 临床肝胆病杂志, 2019, 35(3): 574-578.

高春会, 苏爱江, 魏广占, 等. 茵栀黄颗粒治疗肿瘤化疗后肝损伤的临床观察[J]. 中国老年保健医学, 2019, 17(3): 51-53.

李佐清. 清热解毒法为主治疗化疗所致肝损害43例疗效观察[J]. 安徽中医临床杂志, 1997, 9(2): 74-75.

陈闯, 张作军. 茵陈蒿汤加味治疗肝动脉插管化疗所致肝损害的对照观察[J]. 中医药研究, 1998(2): 3-5.

吴先平. 关于中西医联合疗法的应用对于减少乳腺癌化疗副反应的影响[J]. 中西医结合心血管病电子杂志, 2016, 4(22): 4-5.

董金材, 王曦, 李凤娇, 等. 酒精性肝损伤研究及中药治疗进展[J]. 辽宁中医杂志, 2019, 46(8): 1772-1779.

杨清煜, 余远鹏, 张义, 等. 中医药治疗肝损伤的研究进展[J]. 湖北民族学院学报(医学版), 2019, 36(4): 46-49.

高月求, 周振华, 单俊杰. 天然多糖抗药物性肝损伤的研究进展[J]. 国际药学研究杂志, 2019, 46(3): 163-170.

邱赛红, 黄湘珺, 黄宇明, 等. 灵芝及其提取物减轻肝损伤作用的研究概况[J]. 湖南中医药大学学报, 2017, 37(4): 461-464.

高清. 中西医结合治疗乳腺癌术后化疗药物性肝损害30例[J]. 上海中医药杂志, 2013, 47(6): 38-40.

耿睿韬, 赵文霞. 中医药治疗药物性肝损伤的研究进展[J]. 中国继续医学教育, 2015, 7(20): 195-196.

吴艳玲, 廉丽花, 南极星. 中药有效成分治疗肝损伤及肝纤维化作用机制的研究进展[J]. 世界华人消化杂志, 2016, 24(30): 4144-4150.

张晓静, 张频, 徐兵河, 等. 吡柔比星单次或分次给药对药代动力学和药物不良反应影响的研究[J]. 癌症进展, 2008, 6(4): 396-401.

宋玲琴, 何建军, 王西京, 等. 乳腺癌术后TC方案辅助化疗的不良反应观察[J]. 现代肿瘤医学, 2011, 19(8): 1568-1570

冯文林, 伍海涛, 罗超华. 白芍总苷在消化系统疾病中的药理研究进展[J]. 时珍国医国药, 2012, 23(7): 1778-1779.

许亚培, 王秀娟. 蒿芩清胆汤临床应用的研究进展[J]. 黑龙江中医药, 2013, 42(3): 74-75.

任红叶, 周永学. 三仁汤临床应用进展[J]. 江西中医药, 2016, 47(10): 77-80.

钟元涛, 赵远红, 吕强. 王氏连朴饮新用治验乳癌化疗与靶向治疗不良反应1则及思考[J]. 中成药, 2019, 41(6): 1479-1480.

Views

下载量

CSCD

Alert me when the article has been cited

提交

Tools

Publicity Resources

Analysis of HUA Baojin's Thought and Experience of "Tonifying Vital Qi and Regulating Qi" in Prevention and Treatment of Cancer

Experience on Discussion and Analysis on Application of Cancer Toxicology Theory

Professor Wei Kaijian's experiences in treating cancer with Fuzheng Qingjie Recipe

SUN Bingyan’s Experience in Treating Cancers of Digestive Tract

Analysis of Clinical Experience of WANG Weiying in the Treatment of Allergic Purpura

Related Author

No data

Related Institution

Guang'anmen Hospital, China Academy of Chinese Medical Sciences

Beijing Hospital of Traditional Chinese Medicine, Capital Medical University

The Second Affiliated Hospital of Fujian University of Traditional Chinese Medicine

Fujian University of Traditional Chinese Medicine

Preventive Treatment Center, Cangzhou Hospital of Integrated Traditional Chinese Medicine-Western Medicine in Hebei Province

⁰