This study summarized Professor WANG Guocai's clinical experience in treating insomnia based on the pathogenesis of blood stasis. He considers that the lingering refractory disease is closely related to blood stasis, blood stasis runs through the whole process of the disease. In terms of the treatment, the main method is promoting blood circulation and removing blood stasis, assisted by supplementing Heart and Spleen, resolving phlegm and regulating Qi, soothing Liver and relieving depression, as well as tranquilizing mind with heavy material. The corresponding cases were attached for sharing with the peers.