Cao Shi-li's Experience of Diagnosis and Treatment of Lupus Nephritis

LI Shi-yi; LIN Yan

doi:10.16367/j.issn.1003-5028.2022.07.0221

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Cao Shi-li's Experience of Diagnosis and Treatment of Lupus Nephritis

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Cao Shi-li's Experience of Diagnosis and Treatment of Lupus Nephritis
1.First Teaching Hospital of Tianjin University of Traditional Chinese Medicine, Tiangjin, China, 300381
2.National Clinical Research Center for Chinese Medicine Acupuncture and Moxibustion, Tianjin, China, 300381
DOI：10.16367/j.issn.1003-5028.2022.07.0221

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LI Shi-yi, LIN Yan. Cao Shi-li's Experience of Diagnosis and Treatment of Lupus Nephritis[DB/OL].（2023-08-01）[2023-11-05].http://cccl-tcm.cacm.org.cn/thesisDetails#10.16367/j.issn.1003-5028.2022.07.0221
DOI：

LI Shi-yi, LIN Yan. Cao Shi-li's Experience of Diagnosis and Treatment of Lupus Nephritis[DB/OL].（2023-08-01）[2023-11-05].http://cccl-tcm.cacm.org.cn/thesisDetails#10.16367/j.issn.1003-5028.2022.07.0221 DOI：

摘要

曹式丽教授认为，肾虚是狼疮性肾炎的发病基础，风邪可诱发或加重蛋白尿，热毒是发病的重要诱因，湿热、瘀血是主要病理因素，贯穿疾病始终。狼疮性肾炎可分为活动期及缓解期，活动期多见风邪为患、热毒炽盛；缓解期以脾肾亏虚表现为主。曹教授治疗缓解期狼疮性肾炎，扶正与祛邪并重，既重补脾益肾以治本，又重祛风、清热、利湿、活血以治标。曹教授认为，狼疮性肾炎治疗的根本目的在于保持络脉通畅，善用虫蚁或藤类药以搜风剔邪，常用药有蝉蜕、白僵蚕、全蝎、地龙、青风藤、鸡血藤、络石藤等；根据病程长短、瘀血轻重选择不同的活血祛瘀药；祛湿不专用淡渗一法，而是三焦分利以祛湿邪，在上芳香化湿，在中燥湿运脾，在下淡渗利湿。LN缓解期，病情相对稳定，曹教授通过健脾益肾以治疗本病，补益脾肾通补兼施，使补而不滞，常用生黄芪、党参、白芍、白术、当归、槲寄生、杜仲等。

Abstract

Professor Cao Shi-li believes that kidney deficiency is the occurrence basis of lupus nephritis (LN); wind pathogen can induce or aggravate proteinuria; heat toxin is an important inducement of the disease; dampness heat and blood stasis are the main pathological factors throughout the disease. In LN active period, wind pathogen and heat toxin are common. The main manifestation in remission period is deficiency of spleen and kidney. Professor Cao's treatment of LN in remission period pays equal attention to strengthening healthy qi and eliminating pathogenic factors. He not only focuses on tonifying the spleen and kidney to cure the root cause, but also dispelling wind, clearing heat, removing dampness and activating blood circulation to treat the manifestations. Professor Cao believes that the fundamental purpose of the treatment of LN is to keep the collaterals unobstructed, and make good use of insects, ants or rattan drugs to eliminate wind pathogen. Commonly used drugs include Chantui (,Periostracum Cicadae,), Baijiangcan (,Bombyx Batryticatus,), Quanxie (,Scorpio,), Dilong (,Pheretima,), Qingfengteng (,Caulis Sinomenii,), Jixueteng (,Caulis Spatholobi,), Luoshiteng (,Caulis Trachelospermi,), etc. He chooses different drugs for promoting blood circulation and removing blood stasis according to the duration of the disease and the severity of blood stasis. He does not use the only method of draining dampness to eliminate dampness, but adopts different methods in triple energizer: In upper energizer, resolving dampness with aromatics is used. In middle energizer, dryness dampness and activating the spleen is used. In lower energizer, draining dampness with bland diuretics is used. In remission period, the condition is relatively stable, so Professor Cao treats the disease root by strengthening the spleen and nourishing the kidney, while tonifying the spleen and kidney for dredging and tonifying together, so that the tonic is not stagnant. Shenghuangqi (,Radix Scutellariae,), Dangshen (,Radix Codonopsis,), Baishao (,Radix Paeoniae Alba,), Baizhu (,Rhizoma Atractylodis Macrocephalae,), Danggui (,Radix Angelicae Sinensis,), Hujisheng (,Herba Visci,), Duzhong (,Cortex Eucommiae,), etc. are often used.

关键词

狼疮性肾炎肾虚湿热瘀血曹式丽

Keywords

lupus nephritis (LN)kidney deficiencydampness heatblood stasisCao Shi-li

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