Diffuse thyroid lesions are the common ultrasound manifestation of hyperthyroidism or hypothyroidism caused by a variety of reasons, including hyperthyroidism, thyroiditis, etc. Academician Tong Xiaolin believes that this type of disease is mainly caused by emotional disorders and presents a development process of "stagnation, blood stasis, deficiency" . For its treatment, attention should be paid to recognizing the cause and pursuing the effect, regulating the states and treating the target. For the state of stagnation of phlegm and fire in its early stage, common selfheal fruit-spike, catclaw buttercup root and common scouring rush herb can clear heat-fire, dissipate phlegm and resolve masses, regulating the state and target at the same time, with the commonly used clinical dosage of common selfheal fruit-spike 30-60 g, catclaw buttercup root 15-30 g, and common scouring rush herb 15 g.