LIAN Fang's Experience on Treating Ovarian Hyperstimulation Syndrome

DONG Li; LIAN Fang; WU Haicui; XIN Xin

doi:10.13192/j.issn.1000-1719.2022.02.007

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LIAN Fang's Experience on Treating Ovarian Hyperstimulation Syndrome

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LIAN Fang's Experience on Treating Ovarian Hyperstimulation Syndrome
1.Shandong University of Traditional Chinese Medicine, Jinan 250014, Shandong, China
2.Affiliated Hospital of Shandong University of Traditional Chinese Medicine, Jinan 250011, Shandong, China
DOI：10.13192/j.issn.1000-1719.2022.02.007

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DONG Li, LIAN Fang, WU Haicui, et al. LIAN Fang's Experience on Treating Ovarian Hyperstimulation Syndrome[DB/OL].（2023-09-15）[2023-11-05].http://cccl-tcm.cacm.org.cn/thesisDetails#10.13192/j.issn.1000-1719.2022.02.007
DOI：

DONG Li, LIAN Fang, WU Haicui, et al. LIAN Fang's Experience on Treating Ovarian Hyperstimulation Syndrome[DB/OL].（2023-09-15）[2023-11-05].http://cccl-tcm.cacm.org.cn/thesisDetails#10.13192/j.issn.1000-1719.2022.02.007 DOI：

摘要

卵巢过度刺激综合征为多发生于辅助生殖技术促排卵后黄体阶段或妊娠早期的医源性并发症之一，其主要病理特征是卵巢增大、全身毛细血管增生和通透性体液渗出、血液浓缩、水电解质平衡失调，常见于多囊卵巢综合征患者。连方教授认为卵巢过度刺激综合征的中医病机是脾肾两虚、水饮停聚，进而影响气血运行可出现气滞血瘀痰阻等病理变化，为本虚标实之证，与脾肾关系密切，可涉及心、肝、肺三脏。其中医治疗以温阳健脾、利水行气为主，佐以活血化瘀，方用参苓白术散合二仙调经方加减；西医治疗应注意及时补充体液以纠正低血容量状态，同时维持水电解质酸碱平衡及血浆胶体渗透压，防止出现肝肾功能障碍、循环衰竭、血栓形成等一系列并发症。连方教授总结多年的临床经验，往往根据患者的个体情况从中西医结合角度预防治疗本病，标本兼顾、病证结合，多能取得显著的临床疗效。

Abstract

Ovarian hyperstimulation syndrome is one of the most common iatrogenic complications in the luteal phase or early pregnancy after assisted reproductive technology. Its main pathological features are ovarian enlargement, systemic capillary hyperplasia and permeability fluid exudation, blood concentration, and imbalance of water and electrolyte balance, often seen in patients with polycystic ovary syndrome. Professor LIAN Fang believes that the pathogenesis of ovarian hyperstimulation syndrome is caused by deficiency of spleen and kidney, water and body fluid retention, and then affects the movement of Qi and blood, which can lead to pathological changes such as Qi stagnation, blood stasis and phlegm obstruction. Among them, the main medical treatment is warming Yang and invigorating spleen, promoting water and Qi, promoting blood circulation and removing blood stasis, Shenling Baizhu Powder (参苓白术散) and Erxian Tiaojing Formula (二仙调经方) are the main prescriptions. In the treatment of Western medicine, we should pay attention to timely supplement body fluid to correct the state of low blood volume, maintain the acid-base balance of water and electrolyte and plasma colloid osmotic pressure, and prevent a series of complications such as liver and kidney dysfunction, circulatory failure and thrombosis. Based on many years of clinical experience, Professor LIAN Fang often prevents and treats the disease from the perspective of integrated traditional Chinese and Western medicine according to the individual situation of patients. Taking into account both specimens and disease syndromes, the treatment can achieve significant clinical efficacy.

关键词

卵巢过度刺激综合征脾肾两虚温阳健脾行气利水连方名医经验

Keywords

ovarian hyperstimulation syndromedeficiency of spleen and kidneywarming Yang and invigorating spleenpromoting Qi and waterLIAN Fangexperience of famous doctors

references

乔杰. 辅助生殖技术促排卵药物治疗共识[M]. 北京: 人民卫生出版社, 2016: 60.

庄广伦. 现代辅助生殖技术[M]. 北京: 人民卫生出版社, 2005: 408.

PFEIFER S, BUTTS S, DUMESIC D, et al. Prevention and treatment of moderate and severe ovarian hyperstimulation syndrome: a guideline[J]. Fertil Steril, 2016, 106: 1634-1647.

姜李乐, 曹国昌, 梁琳琳, 等. 卵巢过度刺激综合征的研究现状[J]. 国际生殖健康·计划生育杂志, 2013, 32(5): 391.

黄荷凤. 现代辅助生育技术[M]. 北京: 人民军医出版社, 2003: 280-282.

连方. 中西医结合生殖医学[M]. 北京: 人民卫生出版社, 2017: 392.

宁琼, 张蒙夏, 曾海涛. 卵巢过度刺激综合征发病机制及预防[J]. 中南医学科学杂志, 2017, 45(2): 189-192.

YOUSSEF M A, VAN DER VEEN F, AL-INANY H G, et al. Gonadotropin-releasing hormone agonist versus HCG for oocyte triggering in antagonist-assisted reproductive technology[J]. Cochrane Database Syst Rev, 2014(10): CD008046

TALEBI C S, ZOSMER A, CARAGIA A, et al. Coasting, embryo development and outcomes of blastocyst transfer: a casecontrol study[J]. Reprod Biomed Online, 2014, 29(2): 231-238.

CHRISTOPOULOS G, VLSMAS A, CARBY A, et al. Gn RH agonist trigger with intensive luteal phase support vs. human chorionic gonadotropin trigger in high responders: an observational study reporting pregnancy outcomes and incidence of ovarian hyperstimulation syndrome[J]. Hum Fertil(Camb), 2016, 19(3): 199-206.

BORGES E, BRAGA D P, SETTI A S, et al. Strategies for the management of OHSS: Results from freezing-all cycles[J]. JBRA Assist Reprod, 2016, 20(1): 8-12.

谈勇.PCOS促排卵合并症的中西医治疗对策[C]//浙江省中医药学会(Zhejiang Association of Chinese Medicine)，杭州市中医院.2011年浙江省中医药学会妇科分会学术年会暨中西医结合防治生殖障碍疾病高级培训班文集. 浙江省中医药学会(Zhejiang Association of Chinese Medicine)，杭州市中医院：浙江省科学技术协会, 2011: 5.

吴迪, 连方. 连方中西医结合治疗卵巢过度刺激综合征验案1则[J]. 湖南中医杂志, 2016, 32(3): 120-122.

LEE T H, LIU C H, HUANG C C, et al. Serum anti-Müllerian hormone and estradiol levels as predictorsof ovarian hyperstimulation syndrome in assisted reproduction technology cycles[J]. Hum Reprod, 2008, 23(1): 160-167.

金晔, 安萍, 张惠娟, 等. 体外受精-胚胎移植过程中卵巢过度刺激综合征发生危险因素分析[J]. 中国煤炭工业医学杂志, 2020, 23(5): 528-532.

李秀芳. 卵巢过度刺激综合征预防及治疗方法的研究进展[J]. 当代医药论丛, 2018, 16(1): 31-33.

宋关书, 刘得智, 门立立. 促性腺激素释放激素拮抗剂联合来曲唑治疗卵巢过度刺激综合征的临床效果观察[J]. 吉林医学, 2020, 41(7): 1620-1622.

祝佩芹, 米立国, 李莲. 中西医结合治疗卵巢度刺激综合征的实验研究[J]. 中国妇幼保健, 2009, 24(19): 2628-2630.

吴胜男, 马娟娟, 张勤华. 补肾活血方治疗中度卵巢过度刺激综合征的临床研究[J]. 中医药导报, 2020, 26(15): 87-90.

罗燕, 陈凌燕, 吴荣珍. 五皮饮方治疗体外受精-胚胎移植术后的卵巢过度刺激综合征的效果[J]. 医学信息, 2020, 33(19): 152-154.

牟珍妮, 刘红根, 乔岩, 等. 针刺联合脐疗治疗中度卵巢过度刺激综合征(脾肾阳虚证)的临床研究[J]. 中国中医急症, 2019, 28(6): 958-960,978.

谈勇. 卵巢过度刺激综合征的辨证论治[J]. 江苏中医药, 2006, 27(3): 13-14.

赵冬梅, 谭丽. 卵巢过度刺激综合征不同治疗方法探究[J]. 医药论坛杂志, 2006, 27(14): 66-67.

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