Objective,2,To summarize Professor Cheng GuoZhong's academic thoughts and experience in clinical diagnosis and treatment of spleen deficiency and wetness hyperactivity type diseases.,Methods,2,By following with the tutor and studying the clinical data of spleen deficiency and dampness syndrome of hyperactivity, the author summarized Professor CHENG Guozhong's aca-demic thoughts and experience in clinical treatment of spleen deficiency and dampness syndrome of hyperactivity from aspects of main pathogenesis trait, prescription drugs and provided the typical medical cases for support.,Results,2,Professor CHEN Guozhong thinks that Lingnan area is easy to suffer from the combination of external dampness and internal dampness because of its unique natural climate, regional environment and local living habits. Most people are in the spleen sub-health state of spleen deficiency and excessive dampness syndrome, which is mainly manifested by gastrointestinal discomfort. Therefore, on the basis of Tiaozhong Yiqi Decoction (调中益气汤) written in ,Spleen and Stomach Theory, Tiaozhong Yiqi Huashi Decoction (调中益气化湿汤) was modified. According to the clinical data of the patients, the four diagnostic methods of traditional Chinese medicine were combined to treat various clinical diseases of spleen deficiency and excess dampness.,Conclusion,2,Professor CHENG Guozhong has rich clinical experience and distinct characteristics in the treatment of spleen deficiency and dampness syndrome of hyperactivity, reflecting the thinking of adjusting measures to local conditions and treating different diseases by one therapy in traditional Chinese medicine and Tiaozhong Yiqi Huashi Decoction has define and reliable curative effect, worthy of reference and learning.